针对宫癌未得到充分查的妇女:将自我抽样和人类乳头瘤病毒检测与战略提醒计划相结合
Sara da Graça Pereira1, Luís Nobre1, Marina Ribeiro1
1Infogene, IPN Aceleradora, Coimbra, Portugal.
European journal of public health
|July 29, 2025
概括
使用自取样套件,人类乳头瘤病毒 (HPV) 检测和个性化推广的综合方法显著改善了未经查的妇女的宫癌查参与率. 这一策略有效地识别了子宫病变,以便早期检测.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 妇科 妇科医生 妇科
背景情况:
- 宫癌 (CC) 查对于减少发病率至关重要,但吸引未经查的人口仍然是一个重大的公共卫生挑战.
- 自取样方法为增加查出席率提供了一个有希望的途径,但它们在查计划中的实际实施面临着障碍.
研究的目的:
- 评估一种多式策略,结合宫性阴道自取样,人类乳头瘤病毒 (HPV) 检测和个性化接触方法.
- 评估这种方法在接触和吸引那些没有参加传统CC查计划的妇女方面的有效性.
主要方法:
- 使用"选择"方法,对687名符合条件的妇女 (30-59岁) 进行了选择性查,这些妇女已逾期进行CC查.
- 参与者获得了家庭自取样套件,使用多种联系策略 (电话,信件) 来鼓励样品返回.
- 高风险HPV (hr-HPV) 阳性病例被转诊进行妇科随访和病变检测.
主要成果:
- 在687名符合条件的妇女中,有307人同意 (44.7%) 和198人提交了有效的样本进行HR-HPV测试 (28.8%).
- 个性化接触,特别是第一次提醒电话,是非常有效的,注册60%的参与者.
- 在12例h-HPV阳性病例中,11例参加了随访,导致确定了6个宫病变.
结论:
- 自我采样,HPV检测和个性化接触的综合策略是可行的,并且有效地提高了未经查的妇女中CC查的普及率.
- 这种干预模型显示了在查计划中填补参与差距的潜力,并促进早期发现宫异常.
- 成功实施可以通过提高早期检测率来减少宫癌的总体发病率.
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