Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Cycloaddition Reactions: Overview01:16

Cycloaddition Reactions: Overview

2.8K
Cycloadditions are one of the most valuable and effective synthesis routes to form cyclic compounds. These are concerted pericyclic reactions between two unsaturated compounds resulting in a cyclic product with two new σ bonds formed at the expense of π bonds. The [4 + 2] cycloaddition, known as the Diels–Alder reaction, is the most common. The other example is a [2 + 2] cycloaddition.
2.8K
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction01:16

[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction

10.7K
The Diels–Alder reaction is an example of a thermal pericyclic reaction between a conjugated diene and an alkene or alkyne, commonly referred to as a dienophile. The reaction involves a concerted movement of six π electrons, four from the diene and two from the dienophile, forming an unsaturated six-membered ring. As a result, these reactions are classified as [4+2] cycloadditions.
10.7K
Cycloaddition Reactions: MO Requirements for Thermal Activation01:16

Cycloaddition Reactions: MO Requirements for Thermal Activation

3.7K
Thermal cycloadditions are reactions where the source of activation energy needed to initiate the reaction is provided in the form of heat. A typical example of a thermally-allowed cycloaddition is the Diels–Alder reaction, which is a [4 + 2] cycloaddition. In contrast, a [2 + 2] cycloaddition is thermally forbidden.
3.7K
Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry01:29

Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry

4.8K
Diels–Alder reactions between cyclic dienes locked in an s-cis configuration and dienophiles yield bridged bicyclic products.
4.8K
Diels–Alder Reaction Forming Cyclic Products: Stereochemistry01:28

Diels–Alder Reaction Forming Cyclic Products: Stereochemistry

4.1K
The Diels–Alder reaction is one of the robust methods for synthesizing unsaturated six-membered rings. The reaction involves a concerted cyclic movement of six π electrons: four π electrons from the diene and two π electrons from the dienophile.
4.1K
Cyclohexenones via Michael Addition and Aldol Condensation: The Robinson Annulation01:27

Cyclohexenones via Michael Addition and Aldol Condensation: The Robinson Annulation

2.3K
Robinson annulation is a base-catalyzed reaction for the synthesis of 2-cyclohexenone derivatives from 1,3-dicarbonyl donors (such as cyclic diketones, β-ketoesters, or β-diketones) and α,β-unsaturated carbonyl acceptors. Named after Sir Robert Robinson, who discovered it, this reaction yields a six-membered ring with three new C–C bonds (two σ bonds and one π bond).
2.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Case Report: Torque teno virus identified in pleural effusion of pediatric severe Mycoplasma pneumoniae pneumonia: diagnostic and therapeutic implications.

Frontiers in pediatrics·2026
Same author

Base-mediated [2+4] annulation of benzothiazolium salts and 2-aminobenzaldehydes: selective synthesis of 2-amino and 2-thio-substituted quinolines.

Chemical communications (Cambridge, England)·2026
Same author

Toward sustainable valorization of red mud: environmental durability and service-life modelling of geopolymers under coupled saline and wet-dry cycling conditions.

Journal of environmental management·2026
Same author

Debranching and OSA esterification of waxy maize starch: effects on nanoparticle properties and emulsion performance.

Food chemistry: X·2026
Same author

Humic acid-mediated oxidation of As(III) by magnetic iron oxides derived from iron sludge: Insights into electron transfer and ROS generation.

Environmental research·2026
Same author

WGCNA reveals dose-dependent responses and molecular regulatory networks of strigolactone-mediated drought mitigation in <i>Astragalus membranaceus</i> var. <i>mongholicus</i>.

Frontiers in plant science·2026
Same journal

3-Methyleneazetidine: a versatile building block for functional and post-modifiable polysulfonamides.

Chemical communications (Cambridge, England)·2026
Same journal

Synthesis of divalent galactosyl and fucosyl spiropyran derivatives for the targeted inhibition of bacterial biofilms.

Chemical communications (Cambridge, England)·2026
Same journal

Emergent cytotoxicity and mitochondrial alterations induced by a heterobimetallic Re(I)/Au(I) complex.

Chemical communications (Cambridge, England)·2026
Same journal

Cyanoacetylation of amines <i>via</i> a traceless cyanoacetyl radical: synthetic access to teriflunomide.

Chemical communications (Cambridge, England)·2026
Same journal

Loading layered double hydroxide nanoarray catalysts on a micro-curved substrate for kinetics-favorable water electrolysis reaction.

Chemical communications (Cambridge, England)·2026
Same journal

Bridging <i>in situ</i> measurements and practical conditions through gas-liquid management for CO/CO<sub>2</sub> reduction.

Chemical communications (Cambridge, England)·2026
查看所有相关文章

相关实验视频

Updated: Sep 13, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of &#945;-Imino &#947;-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

7.0K

迪奥马化 [4+2] 循环添加用于构建桥接的多环乳酸盐.

Qile Wu1, Jingyi Chen1, Haoxian Wu1

  • 1School of Environmental and Chemical Engineering, Wuyi University, Jiangmen 529020, China. chenxiuwen2010@126.com.

Chemical communications (Cambridge, England)
|July 29, 2025
PubMed
概括
此摘要是机器生成的。

这项研究引入了一种无金属的催化系统,用于在单个步骤中从异诺林和马莱胺衍生物中合成复杂的多环乳酸盐. 这种高效的昂贵化策略避免了过渡金属,并实现了高选择性.

更多相关视频

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
07:36

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Published on: November 9, 2019

8.1K
Solid-phase Synthesis of [4.4] Spirocyclic Oximes
05:15

Solid-phase Synthesis of [4.4] Spirocyclic Oximes

Published on: February 6, 2019

6.9K

相关实验视频

Last Updated: Sep 13, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of &#945;-Imino &#947;-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

7.0K
Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
07:36

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Published on: November 9, 2019

8.1K
Solid-phase Synthesis of [4.4] Spirocyclic Oximes
05:15

Solid-phase Synthesis of [4.4] Spirocyclic Oximes

Published on: February 6, 2019

6.9K

科学领域:

  • 有机化学 有机化学
  • 催化剂是一种催化剂.
  • 合成方法论 合成方法论

背景情况:

  • 无金属催化对于可持续合成至关重要.
  • 开发到复杂的多循环乳糖的高效路径仍然是一个挑战.
  • 异二醇衍生物是药物化学中的有价值的支架.

研究的目的:

  • 为 [4+2] 循环添加反应开发一种新的无金属催化系统.
  • 为了实现结构复杂的桥梁多环乳酸的单步合成.
  • 通过脱氧化实现3化异类素的功能化.

主要方法:

  • 一种三元组合的双重循环反应,涉及异诺林和马莱胺衍生物.
  • 使用一种无金属的催化系统.
  • 采用一个昂贵的罗马化战略.

主要成果:

  • 成功地在一个步骤中构建了桥接的多循环乳糖.
  • 形成C-N,C-O和C-C债券.
  • 在C1,N2,C3和C4位置实现了三化异类的功能化.
  • 证明了异常的化学选择性和区域选择性.
  • 高原子和步骤经济.

结论:

  • 开发的无金属系统为复杂的多环乳酸提供了有效的途径.
  • 这种昂贵的芳香化策略为有机合成提供了一种可持续和选择性的方法.
  • 该方法允许对异诺林支架的多功能功能化.