结肠直肠内镜全厚切除:一个葡萄牙的多中心经验,基于回顾性队列
Raquel R Mendes1, André Mascarenhas1, João Correia2
1Gastroenterology Department, Unidade Local de Saúde de Lisboa Ocidental, Lisbon, Portugal.
GE Portuguese journal of gastroenterology
|July 29, 2025
概括
内镜全厚切除 (EFTR) 有效治疗复杂的结直肠病变. 这项研究表明,EFTR在现实实践中具有很高的成功率和可接受的安全率.
科学领域:
- 胃肠病学 胃肠病学
- 内視鏡外科手術 內視鏡外科手術
- 结肠直肠手术 结肠直肠手术
背景情况:
- 内镜全厚切除 (EFTR) 是用于复杂结直肠病变的最小侵入性技术.
- 已公布的数据显示,EFTR技术成功率为89%,R0切除率为79%,不良事件率为12%.
研究的目的:
- 总结9个葡萄牙中心EFTR的疗效和安全性.
- 为了评估手术成功,R0切除和结直肠EFTR的不良事件.
主要方法:
- 多中心,不受控制的,回顾性研究.
- 包括从2017年3月到2023年9月的129次结直肠EFTR手术.
- 评估技术成功,R0切除,治愈切除,不良事件和复发.
主要成果:
- 技术上的成功率为88.4% (114/129).
- R0和治疗切除率分别为75.9%和58.0%.
- 13.2% (17/129) 发生了不良事件,其中5.4%需要手术;局部复发率为5.4%.
结论:
- 结肠直肠EFTR对于精心挑选的复杂病变非常有用.
- 该技术显示了可接受的不良事件率和手术干预需求.
- 现实世界的数据支持EFTR在管理具有挑战性的结直肠疾病中的实用性.
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