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Updated: May 12, 2026

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在CAR-T细胞治疗后,眼部不良事件的发生率较低

Tara Murty1, Karen M Wai1, Ehsan Rahimy1

  • 1Byers Eye Institute, Stanford University, Palo Alto, CA, USA.

Ocular oncology and pathology
|July 29, 2025
PubMed
概括

化学抗原受体 (CAR) -T细胞疗法在治疗后六个月内表现出罕见的眼部不良反应 (o-AEs). 没有先前存在的眼睛疾病的患者通常不需要例行查,除非出现症状.

关键词:
细胞疗法是一种细胞疗法.化学抗原受体 T 细胞免疫治疗是一种免疫疗法.淋巴瘤是一种淋巴瘤.在瘤学瘤学.

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Ophthalmic Drug Delivery Systems01:23

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Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...