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外科医生对手术前炎症性肠病药物和术后并发症的知识,态度和实践
Noura Alhassan1, Abdullah Nasser Alnwdel2, Mohammed Basem Beyari3
1Colorectal Research Chair, Department of Surgery, College of Medicine, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.
许多外科医生担心IBD手术前的生物安全性,但有证据表明它们是安全的. 这种知识差距可能导致停止治疗,增加疾病爆发风险.
科学领域:
- 胃肠病学和肝病学 胃肠学和肝病学
- 手术瘤学手术瘤学
- 免疫学 免疫学 免疫学
背景情况:
- 生物药物,特别是抗TNF药物,已经彻底改变了炎症性肠病 (IBD) 的管理.
- 临床医生仍然担心IBD患者的生物药物的术后安全性.
研究的目的:
- 评估沙特外科医生的知识,态度和实践,涉及生物疗法的IBD患者的手术前管理.
- 确定当前证据和临床实践之间的差距,以管理在使用生物药物时接受手术的IBD患者.
主要方法:
- 对115名具有IBD管理经验的全科医生和结直肠外科医生进行了横截面调查.
- 数据分析的重点是对生物制剂,皮质类固醇和免疫调节剂对伤口愈合和术后并发症的影响的看法.
主要成果:
- 显著的大多数 (74.4%) 的外科医生认为生物制剂对伤口愈合有害,这与现有证据相反.
- 虽然皮质类固醇被认为具有不良影响,免疫调节剂被认为是安全的,但注意到人们更喜欢在手术前逐渐减少生物药物和皮质类固醇.
- 结肠直肠外科医生比一般外科医生更好地遵守基于证据的指导方针,他们对生物风险表示更大的担忧.
结论:
- 在沙特外科医生对生物药物治疗IBD患者的术后管理中,证据和实践之间存在着显著的差异.
- 一般外科医生对生物制剂的担忧,导致不必要的停止,可能会增加疾病爆发的风险.
- 优化手术结果需要有针对性的教育和加强多学科合作,以使实践与证据保持一致.
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