药剂师主导干预在慢性疾病中对药物坚持的有效性:随机对照试验的系统审查
Lubna Farhana1, Fima Perdani Rahayu1, Shofuro Sholihah1
1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia.
Patient preference and adherence
|July 29, 2025
概括
药剂师主导的干预措施,包括咨询和量身定制的方法,改善了慢性疾病的药物坚持. 进一步的研究应该集中在个性化策略上,以提高效率和患者的结果.
科学领域:
- 医药护理 医药护理 医药护理
- 公共卫生 公共卫生
- 慢性疾病管理 慢性疾病管理
背景情况:
- 药物不良服药严重影响慢性疾病的管理,导致严重的并发症和过早死亡.
- 药剂师,作为药品护理的关键提供者,是开发应对抗不服药的干预措施的重要组成部分.
- 这项研究系统地评估了药剂师主导干预措施的有效性,以提高慢性疾病患者的药物服药能力.
研究的目的:
- 系统地审查和分析药剂师主导的干预措施对慢性疾病患者药物服药的有效性.
- 确定药剂师使用的常见干预策略及其对遵守率的影响.
- 评估评估这些干预措施的随机对照试验 (RCT) 证据的质量.
主要方法:
- 在PubMed和EBSCO进行了全面的文献搜索,搜索到2024年10月发表的RCT.
- 研究的重点是慢性疾病,如高血压,糖尿病和心血管疾病,不包括急性或精神健康状况.
- 偏差风险2 (RoB2) 工具被用来批判性地评估所包含的研究的方法质量.
主要成果:
- 在75项确定的研究中,有26项符合纳入标准,其中很大一部分来自欧洲 (42%).
- 干预类型包括咨询 (53.8%),定制方法 (26.9%),基于技术的监测 (3.85%) 和多次干预 (15.4%).
- 大多数研究 (69.2%) 报告说,药剂师主导的干预措施与改善药物坚持之间存在显著的积极关联,主要通过自我报告问卷进行测量.
结论:
- 药剂师主导的干预措施,包括咨询和量身定制的策略,显示出改善慢性疾病的药物服药能力的潜力.
- 这些干预措施的有效性是可变的,受干预类型和用于粘附测量的方法的影响.
- 未来的研究应该优先考虑针对患者的专门干预措施,以解决针对患者的具体障碍,以优化效率,资源配置和成本效益.
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