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Updated: Sep 13, 2025

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
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In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol

Published on: December 30, 2016

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干扰素调节因子4与剂量相关,通过调节小鼠的染色质可访问性来控制外围Treg细胞分化和稳态

Leonie Caroline Voß1, Constantin Schmidt1,2, Aenne Harberts1,2,3

  • 1Department for Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Frontiers in immunology
|July 29, 2025
PubMed
概括

干扰素调节因子4 (IRF4) 对于调节性T (Treg) 细胞分化和恒温至关重要. 失去IRF4会损害Treg细胞的成熟和功能,影响免疫耐受性.

关键词:
福克斯P3P3 在线播放干扰素调节因子4 干扰素调节因子在T细胞,T细胞.对转化酶可访问的染色体 (ATAC) 测序的测定.监管T细胞的监管性T细胞

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