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功能性纳米材料用于增强瘤光热疗法 - 机制和应用

Xiaoling Han¹, Guohai Feng², Xiaoman Li¹

¹Department of Pharmacy, Jilin Medical University, Jilin, China.

Frontiers in pharmacology

|July 29, 2025

概括

光热疗法 (PTT) 使用激光光产生热量,有效地杀死瘤细胞. 本综述涵盖了用于先进PTT的纳米材料,提高瘤向和治疗效率.

科学领域:

生物医学工程生物医学工程
纳米技术纳米技术
在瘤学瘤学.

背景情况:

光热疗法 (PTT) 是一个有前途的微创性癌症治疗方法.
PTT利用激光照射将光转化为热来进行瘤细胞切除.
高效的光热转换纳米材料对于PTT有效性至关重要.

研究的目的:

审查PTT的各种光热转换纳米材料.
总结它们的特征,性能和治疗效果.
探索PTT的进步,以改善癌症治疗.

主要方法:

在PTT中使用的无机和有机纳米材料的审查.
对聚多巴胺 (PDA),半导体纳米粒子 (SNPs),金 (Au) 纳米材料,纳米片 (PdNs) 和碳纳米材料等纳米材料的分析.
针对向药物输送和组合治疗的功能性修改的摘要.

主要成果:

关于PTT的PDA,SNP,Au,PdN和碳纳米材料的详细概述.
突出了瘤向,无活化和整体治疗效果的优势.
对纳米光热疗法机制的探索.

结论:

纳米材料显著提高PTT性能和瘤向.
化学修饰使得有针对性的药物输送和组合疗法成为可能.
持续的开发有望提供更安全,更有效和最少侵入性的瘤治疗方法.

关键词:

纳米材料是一种纳米材料.纳米光热剂是一种纳米光热剂.光热疗法是一种光热疗法.聚合物纳米粒子的聚合物纳米粒子.瘤治疗的治疗方法

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