细节中的魔鬼:分析初级扩散性慢性鼻炎组织样本的详细组织病理报告 - - 临床和病理学的视角
Tejpal Singh Bedi1, Shashi Shekhar Prasad2, Saurabh Mahajan3
1Department of ENT, Military Hospital Meerut, Meerut, Uttar Pradesh 250001 India.
概括
手术前使用的类固醇不会影响慢性鼻炎的诊断. 然而,缺乏中性友的透物,预测在接受手术的患者中复发.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 病理学 病理学 病理学
背景情况:
- 慢性鼻炎 (CRS) 涉及鼻腔通道和鼻炎症.
- 诊断遵循2020年欧洲鼻炎和鼻的立场文件 (EPOS2020) 的指导方针.
- 埃索诺菲尔CRS被定义为>10埃索诺菲尔/高功率场 (HPF).
研究的目的:
- 为了确定手术前的类固醇是否会影响eosinophilic与非eosinophilic的CRS诊断.
- 为了确定CRS复发的病理预测因素.
主要方法:
- 对53名患者进行了回顾性研究.
- 患者根据手术前的口服类固醇使用被分为类固醇和非类固醇组.
- 对乙氨基酸细胞数量和其他病理参数的分析.
主要成果:
- 在手术前使用类固醇没有显著影响CRS的eosinophilic诊断.
- 缺少中性友性透物被确定为复发的预后因素.
- 这些发现与印度人口有关,在次大陆之前的研究有限.
结论:
- 手术前使用的类固醇不会改变基于乙氨基酸细胞计数的CRS分类.
- 缺少中性线性透是潜在的CRS复发的一个关键指标.
- 这项研究为印度次大陆提供了关于CRS诊断和预后的新见解.
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