喉的先天性desmoid瘤:一个治疗挑战
相关实验视频
Updated: Sep 13, 2025
07:30
Learning Modern Laryngeal Surgery in a Dissection Laboratory
Published on: March 18, 2020
8.2K
Saúl Astray Gómez1, Santiago Almanzo1,2, Adrián Hernández Moya3
1Department of Otorhinolaryngology, Hospital Universitari i Politecnic La Fe, Valencia, Spain.
概括
婴儿的desmoid瘤可能会危及生命. 针对性疗法,如铁氨酸激酶抑制剂,有效控制了儿科患者的喉内瘤,提供了不那么侵入性的治疗选择.
科学领域:
- 儿科瘤学 儿科瘤学
- 手术病理学手术病理学
- 药理学研究 药理学研究
背景情况:
- 质瘤虽然是良性的,但当它影响到重要结构时,可能会危及生命.
- 儿科病例存在独特的挑战,原因是潜在的长期后果和缺乏标准化治疗.
- 喉内的瘤很少见,并且可能导致婴儿的呼吸系统严重受损.
研究的目的:
- 报告一个新生儿喉内瘤的病例.
- 评估系统化疗与伊马替尼布联合治疗儿科患者的疗效.
- 为突出针对性治疗作为一个切实可行的替代手术治疗儿科desmoid瘤.
主要方法:
- 诊断工作包括内镜和计算机断层扫描 (CT) 用于喉瘤的识别.
- 通过活检通过组织病理学确认desmoid瘤.
- 使用全身化疗和伊马替尼布 (一种氨酸激酶抑制剂) 的治疗.
主要成果:
- 患者是一名一个月大的男性,出现呼吸困难和.
- 诊断证实了一个喉的desmoid瘤.
- 结合化疗和伊马替尼布导致瘤大小的稳定.
- 由于儿科患者患病率高的风险,手术被认为不适合.
结论:
- 系统化疗和伊马替尼布在控制新生儿喉皮瘤生长方面表现出有效性.
- 向疗法,特别是氨酸激酶抑制剂,为治疗影响关键区域的儿科desmoid瘤提供了一个有希望的,不那么病态的替代方案.
- 这种方法可以规避与婴儿手术切除相关的显著发病率.
相关概念视频
01:21Larynx
2.1K
The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
2.1K
01:22Trachea
2.7K
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
2.7K