Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Ultra-Sensitive Wireless Capacitive Nanocomposite-Based Pressure Sensors for Health Monitoring.

Advanced materials technologies·2026
Same author

Highly Stable Quasi-Solid-State Sodium Batteries via Facile Grain Boundary Engineering.

ACS applied materials & interfaces·2026
Same author

Behavioral relevance of category selectivity revealed by human ECoG data.

PloS one·2025
Same author

Development and evaluation of gluconic acid-targeted liposomal doxorubicin for enhanced anti-tumor activity in colon cancer.

Journal of pharmaceutical sciences·2025
Same author

Enhancing the immunomodulatory osteogenic properties of Ti-Mg alloy by Mg<sup>2+</sup>-containing nanostructures.

Regenerative biomaterials·2024
Same author

Protective effects of betanin, a novel acetylcholinesterase inhibitor, against H<sub>2</sub>O<sub>2</sub>-induced apoptosis in PC12 cells.

Molecular biology reports·2024

相关实验视频

Updated: Sep 13, 2025

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive
06:40

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive

Published on: September 27, 2013

14.9K

设计用于可植入的大脑机器接口的烯涂层.

Saman Ebrahimibasabi1, Maryam Golshahi2, Naghmeh Shahraki2

  • 1Materials Science and Engineering, School for Engineering of Matter, Transport and Energy, Arizona State University Tempe AZ 85287 USA hamed.arami@asu.edu.

RSC advances
|July 29, 2025
PubMed
概括

研究人员通过结合粘附促进剂和热处理,优化了用于植入式脑机接口 (BMI) 的烯涂层. 这提高了涂层的稳定性和粘附性,这对于设备的长期性能和生物相容性至关重要.

更多相关视频

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
08:54

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

10.9K
Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes
06:39

Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes

Published on: June 8, 2022

2.5K

相关实验视频

Last Updated: Sep 13, 2025

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive
06:40

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive

Published on: September 27, 2013

14.9K
Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
08:54

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

10.9K
Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes
06:39

Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes

Published on: June 8, 2022

2.5K

科学领域:

  • 生物材料科学 生物材料科学
  • 神经工程是神经工程.
  • 表面化学 表面化学

背景情况:

  • 烯是封装可植入生物电子设备的有前途材料,因为它具有生物相容性和化学稳定性.
  • 烯的一个主要限制是它对无机基板的粘附性差,阻碍了设备的长期可靠性.
  • 增强烯粘附对于开发强大的植入式脑机接口 (BMIs) 至关重要.

研究的目的:

  • 调查沉积前和沉积后的处理方法,以改善可植入BMI的帕利烯涂层粘附性和稳定性.
  • 为了确定粘附促进和热处理的最佳条件.
  • 评估优化涂层对设备性能和生物相容性的影响.

主要方法:

  • 使用了不同度的3- ((trimethoxysilyl) propyl-methacrylate作为一个粘附促进剂.
  • 在不同温度下应用了沉积后热处理.
  • 评估涂层稳定性使用加快老化试验在87°C下7天.
  • 评估的细胞毒性和体内生物相容性.
  • 进行FTIR和EDS分析以表征化学变化.
  • 进行了数值分析,以评估对电气性能的影响.

主要成果:

  • 通过150°C的热处理和适当的粘附促进度,可以达到最佳的粘附和稳定性.
  • 热处理增加了烯的结晶性,提高了化学稳定性,减少了分层和微裂.
  • 较高的粘附促进剂度增强了粘附力,特别是在150°C时.
  • 烯涂层保留和增强了可植入设备中的无线合.
  • 优化的烯涂层在体内证明改善了大脑的兼容性和细胞活力.

结论:

  • 协同的沉积前和沉积后处理显著提高了可植入BMI的帕利粘附性和稳定性.
  • 优化的烯涂层提高了设备的可靠性,电性能和生物相容性.
  • 这项研究提供了一种系统的方法来优化用于先进神经技术的烯封装.