在墨西哥人口中通过人体测量和生化指数进行心脏代谢风险评估
Luz Quirino-Vela1, Miguel Mayoral-Chavez1, Yobana Pérez-Cervera1,2
1Centro de Investigación Facultad de Medicina UNAM-UABJO, Facultad de Medicina y Cirugía, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca, Mexico.
Frontiers in endocrinology
|July 29, 2025
概括
非传统的人类指数比传统措施更好地识别墨西哥成年人的心脏代谢风险因素. 这些可访问的工具有助于在资源有限的环境中提前检测高风险个体.
科学领域:
- 心脏病学 心脏病学
- 代谢健康 代谢健康
- 人类测量学 人类测量学.
背景情况:
- 肥胖和高血压等心脏代谢风险 (CMR) 因素对全球健康问题作出了重大贡献.
- 目前用于肥胖和胰岛素抵抗的诊断方法通常昂贵且难以获得.
- 传统的人类测量方法在预测CMR和解释代谢功能障碍方面存在局限性.
研究的目的:
- 评估和比较15种传统和非传统的人类测量和生化指数的诊断准确性,以确定墨西哥成年人中CMR因子.
- 为了确定非传统指数是否比CMR评估的传统措施提供更高的诊断性能.
主要方法:
- 来自2022年国家健康和营养调查 (ENSANUT) 的1,876名墨西哥成年人 (20-80岁) 的数据分析.
- 计算各种人类指数 (例如BMI,WHtR,BRI) 和生化指数 (例如HOMA-IR,TG).
- 使用的接收器操作特征 (ROC) 曲线分析用于诊断性能评估,以性别分层分析.
主要成果:
- 非传统指数显示肥胖和CMR检测的诊断性能优越.
- TG*BMI (AUC=0.972) 和 BRI (AUC=1.000) 分别显示出对肥胖和CMR的高准确性.
- 最佳切线值因性别而异,但歧视能力保持一致.
结论:
- 非传统的人类指数,特别是那些结合了代谢和人类指数数据的指数,优于传统的BMI基于CMR分层在墨西哥成年人的评估.
- 这些可访问和具有成本效益的指数有助于提前识别高风险个体,特别是在资源有限的环境中.
- 需要进一步的研究来验证这些发现,并建立特定人群的参考值.
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