使用proniosomes使用发酵橄叶盐水中氧醇提取物的纳米封装
Pınar Kadiroglu1, Betül Kılınçlı1, Ceren Ilgaz1
1Department of Food Engineering, Adana Alparslan Türkeş Science and Technology University, Adana, Türkiye.
Journal of the science of food and agriculture
|July 29, 2025
概括
橄叶提取物被封装在proniosomes中,增强其稳定性和安全性. 这种纳米技术方法改善了从橄叶中提取的生物活性化合物的食品应用的利用.
科学领域:
- 食品科学与技术 食品科学与技术
- 纳米技术 纳米技术
- 药理学 药理学是指药理学的学科.
背景情况:
- 橄叶含有具有健康益处的生物活性化合物.
- 这些化合物的有限生物可用性和稳定性限制了它们的使用.
- 纳米载体系统为增强其性能提供了一个有前途的解决方案.
研究的目的:
- 开发和表征用于封装橄叶提取物的proniosomes.
- 为了评估proniosome-loaded提取物的稳定性,安全性和有效性.
主要方法:
- 对旋转速度和温度进行优化的proniosome配方.
- 粒子大小,泽塔潜力和同质性分析.
- 在体外细胞毒性测定 (HEK293T细胞) 和体内斑马鱼测定.
主要成果:
- 最佳的proniosome配方实现了81.20%的封装效率.
- 质子体表现出稳定的粒子大小 (188.6248.9 nm) 和泽塔电位 (~-30 mV).
- 与自由提取物相比,proniosomal提取物显示出增强的安全性和稳定性.
结论:
- 基体封装显著提高了橄叶提取物的稳定性和安全性.
- 这种纳米技术驱动的方法支持可持续的食品创新.
- 这些发现为先进的植物性食品配方铺平了道路.
相关概念视频
01:30Peroxisomes
Peroxisomes and mitochondria are two important oxygen-utilizing organelles in eukaryotic cells. Mitochondria carry out cellular respiration—the process that converts energy from food into ATP. Peroxisomes carry out a variety of functions, primarily breaking down different substances, such as fatty acids.The peroxisome is a single membrane-bound cellular organelle that can perform several different functions, including lipid metabolism and chemical detoxification. The enzymes within peroxisomes...
00:43Pinocytosis
Cells use energy-requiring bulk transport mechanisms to transfer large particles, or large amounts of small particles, into or out of the cell. The cells envelop the particles in spherical membranes called vesicles or vacuoles. Vesicles that transport material into the cell are built from the cell membrane. These vesicles encapsulate external molecules and transport them into the cell in a process called endocytosis.