身体活动的变化与2型糖尿病的风险:来自全国前性队列研究的发现
Zehua Wang1, Aiping Zhao1, Chenxing Ma1
1Department of Endocrinology, Tangshan Central Hospital, Tangshan City, Hebei Province, China.
Endokrynologia Polska
|July 29, 2025
概括
高体力活动变化率 (PAVar) 增加了老年人2型糖尿病 (T2DM) 的风险. 保持一致的体力活动和充足的睡眠对于预防糖尿病至关重要.
科学领域:
- 老年学是一门学科.
- 代谢健康 代谢健康
- 流行病学 流行病学
背景情况:
- 身体活动变异性 (PAVar) 是代谢健康的一个新兴因素.
- 了解PAVar对2型糖尿病 (T2DM) 的影响对于老年人群至关重要.
研究的目的:
- 调查身体活动变化 (PAVar) 与患2型糖尿病 (T2DM) 的风险之间的关联.
- 探索睡眠时间在PAVar-T2DM关系中的调解作用.
主要方法:
- 长度队列研究使用中国健康与退休长度研究 (CHARLS) 数据 (2011-2020).
- 分析了3970名参与者,按身体活动变化率 (PAVar) 四分位数进行分类.
- 考克斯的比例危险模型和调解分析,以评估T2DM风险和睡眠时间的影响.
主要成果:
- 较高的PAVar与T2DM风险增加有显著的关联.
- 在最高PAVar四分位数中的个人显示T2DM风险增加了70% (HR: 1.70,95%CI: 1.54-1.88).
- 睡眠时间介于PAVar对T2DM风险的影响的18.5%.
结论:
- 增加的体力活动变性 (PAVar) 构成2型糖尿病 (T2DM) 的重大风险.
- 促进持续的体力活动和足够的睡眠对于老年人T2DM预防至关重要.
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