在持续的肌肉骨疼痛期间,先前使用的可塑性会触发不同的个体皮质运动反应
Anna M Zamorano1,2, Boris Kleber2, Enrico De Martino1
1Center for Neuroplasticity and Pain (CNAP), Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
Pain
|July 29, 2025
概括
之前的运动经验,就像音乐家一样,可以通过增强依赖使用的可塑性来防止长时间的疼痛. 这表明个人的运动背景影响疼痛感知和进展.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 疼痛研究 疼痛研究
背景情况:
- 运动重复对于运动康复和可塑性至关重要.
- 之前的运动经验对疼痛发展的影响还未得到充分研究.
研究的目的:
- 调查先前存在的依赖使用的可塑性如何影响长期肌肉骨疼痛的发展.
- 为了比较疼痛对音乐家和非音乐家运动系统可塑性的影响.
主要方法:
- 经磁刺激 (TMS) 评估了音乐家和非音乐家的皮质脊髓刺激能力.
- 测量包括休息运动值 (RMT),运动唤起的潜力 (MEP) 和第一个背内骨肌 (FDI) 的运动图特征.
- 使用神经生长因子 (NGF) 注射诱导长时间的疼痛.
主要成果:
- 与基线相比,非音乐家在NGF注射后显示运动图体积减少和疼痛强度增加.
- 音乐家的运动地图已经较小,在疼痛诱导时没有显著变化.
- 音乐家的运动地图变化与音乐训练持续时间相关.
结论:
- 从运动训练中预先存在的依赖使用的可塑性可以减轻疼痛对运动系统的影响.
- 之前的运动经验有助于疼痛反应的个体差异.
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