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相关概念视频

Proteomics01:33

Proteomics

7.9K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.9K
Protein Networks02:26

Protein Networks

4.1K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.1K
Protein Families02:47

Protein Families

15.8K
Protein families are groups of homologous proteins; that is, they have similarities in amino acid sequences and three-dimensional structures. Protein families usually occur because of gene duplication, where an additional copy of a gene is inserted into the genome of an organism.   Mutations that change the amino acids but still allow the protein to be properly synthesized, will lead to new protein family members.   If these new proteins contain similar amino acids in key...
15.8K
Protein-protein Interfaces02:04

Protein-protein Interfaces

13.3K
Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
13.3K
Protein and Protein Structure02:15

Protein and Protein Structure

81.4K
Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme...
81.4K
Protein Organization01:24

Protein Organization

7.1K
Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence....
7.1K

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相关实验视频

Updated: Sep 13, 2025

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames
07:38

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames

Published on: April 11, 2019

12.9K

使用MoonProt数据库来了解蛋白质功能

Constance J Jeffery1

  • 1Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL, USA. cjeffery@uic.edu.

Methods in molecular biology (Clifton, N.J.)
|July 29, 2025
PubMed
概括
此摘要是机器生成的。

MoonProt数据库有助于研究人员识别月光蛋白,这些蛋白质可以执行多种功能. 这种资源有助于预测蛋白质功能,通过对这些多功能蛋白质及其特征进行分类.

关键词:
这是一种DNA结合蛋白质.数据库数据库数据库是一个数据库.酵素酶是一种酶.月亮Prot数据库 月亮Prot数据库月亮照明蛋白质的月亮照明蛋白质多功能蛋白质多功能蛋白质蛋白质的功能蛋白质的功能蛋白质功能的预测和预测这是一种RNA结合蛋白.

更多相关视频

A Protocol for Computer-Based Protein Structure and Function Prediction
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A Protocol for Computer-Based Protein Structure and Function Prediction

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An Integrated Approach for Microprotein Identification and Sequence Analysis
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An Integrated Approach for Microprotein Identification and Sequence Analysis

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相关实验视频

Last Updated: Sep 13, 2025

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames
07:38

Mass Spectrometry-Based Proteomics Analyses Using the OpenProt Database to Unveil Novel Proteins Translated from Non-Canonical Open Reading Frames

Published on: April 11, 2019

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A Protocol for Computer-Based Protein Structure and Function Prediction
16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

68.9K
An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

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科学领域:

  • 生物化学 生物化学
  • 分子生物学分子生物学
  • 生物信息学是一种生物信息学.

背景情况:

  • 由于月光蛋白,预测蛋白质功能具有挑战性,这些蛋白质从单个多链中表现出多个不同的功能.
  • 已知500多种月亮蛋白质,突出显示了将单个功能分配给蛋白质的复杂性.
  • MoonProt数据库作为这些多功能蛋白质信息的集中资源.

研究的目的:

  • 为了证明 MoonProt 数据库用于识别已知的月光蛋白的实际实用性.
  • 为了指导用户识别基于序列同质性的潜在月光蛋白.
  • 促进发现具有特定属性的月光蛋白质,包括生物体的起源,功能和疾病关联.

主要方法:

  • 使用MoonProt数据库查询特定的蛋白质或蛋白质家族.
  • 采用序列同质性搜索来识别潜在的月光候选人.
  • 根据生物体,功能和疾病参与过数据库,以找到具有所需特征的蛋白质.

主要成果:

  • MoonProt数据库提供了一种系统的方法来识别和表征月光蛋白.
  • 用户可以有效地确定一个感兴趣的蛋白质是否是一个记录的月光灯.
  • 该数据库可以探索涉及各种生物过程和疾病的月光蛋白.

结论:

  • MoonProt数据库对于研究蛋白质功能和月光现象的研究人员来说是一个宝贵的工具.
  • 有效利用数据库可以促进我们对蛋白质多功能性及其在生物学和医学方面的影响的理解.
  • 该资源支持识别新型月光蛋白及其在健康和疾病中的作用.