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接受甲状腺手术的患者在手术前生活质量不佳
Juha Honkanen1, Krisztina Molnár2, Tuomo Karhumaa2
1Oulu University Hospital and University of Oulu, Kajaanintie 50, Oulu, 90220, Finland. juha.honkanen@pohde.fi.
Journal of endocrinological investigation
|July 29, 2025
概括
接受甲状腺手术的患者在手术前报告生活质量 (QoL) 降低. 年龄较小,抑郁症和语音问题等因素与不良的QoL有关,无论癌症诊断如何.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 生活质量研究 研究 生命质量研究
背景情况:
- 甲状腺手术治疗各种疾病,如,恶性瘤和甲状腺功能过高.
- 以前的研究强调了术后生活质量 (QoL) 的改善.
- 有限的数据存在于进行甲状腺切除术的不同患者队伍的手术前 QoL.
研究的目的:
- 在预定进行甲状腺手术的患者中评估手术前的 QoL.
- 确定与手术前 QoL 降低相关的风险因素.
- 在患有甲状腺癌/疑似恶性瘤的患者和具有非癌症迹象的患者之间比较QOL.
主要方法:
- 对204名接受甲状腺切除或带切除术的患者进行前性研究.
- 在使用RAND-36,ThyPRO-39,贝克抑郁症目录 (BDI) 和语音障碍指数 (VHI) 评估手术前的QOL.
- 统计分析包括曼 - 惠特尼U,奇平方测试和后勤回归.
主要成果:
- 甲状腺手术患者报告的QoL低于芬兰普通人口.
- 在癌症和非癌症患者组之间没有观察到显著的QOL差异.
- 手术前质量低下与年龄较小 (<65岁),BDI/VHI得分较高,BMI升高和呼吸障碍有关.
结论:
- 在接受甲状腺手术的患者中,无论诊断如何,手术前的 QoL 都显著降低.
- 与非恶性甲状腺疾病患者相比,甲状腺癌患者的 QoL 并没有变得更差,这与假设相反.
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