儿童性结肠炎中的脑血管血栓:一个病例报告
Naire Sansotta1, Fabiana Di Stasio2, Angela Amoroso1
1Pediatric Hepatology, Gastroenterology and Transplantation, Papa Giovanni XXIII Hospital, 24127 Bergamo, Italy.
Reports (MDPI)
|July 29, 2025
概括
大脑血栓 (CT) 是儿科炎症性肠病 (IBD) 的严重并发症. 早期诊断和使用低分子量肝素 (LMWH) 的治疗对于管理这种疾病和改善患者的治疗结果至关重要.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 儿科神经学 儿科神经学
- 血栓形成研究研究
背景情况:
- 炎症性肠病 (IBD) 与静脉血栓塞栓症 (VTE) 的风险增加有关.
- 大脑血栓 (CT) 是儿科IBD患者中最常见的VTE表现.
- 目前关于儿童IBDCT的数据有限.
研究的目的:
- 要突出发生和管理的脑血栓在一个小儿科患者性结肠炎.
- 强调早期诊断和治疗CT在儿科IBD中的重要性.
主要方法:
- 一个12岁男孩患有性结肠炎,出现头痛和吐的病例报告.
- 脑静脉血栓的诊断通过脑磁共振扫描得到证实.
- 治疗开始时使用低分子量肝素 (LMWH),随后服用12个月的抗凝药.
主要成果:
- 该患者在IBD爆发后被诊断出脑静脉血栓症.
- 最初用LMWH治疗导致随访MRI时血栓形成的部分解决.
- 长期的抗凝血疗法进行了12个月的治疗.
结论:
- 大脑静脉血栓形成是儿科IBD患者的重大并发症.
- 患有IBD的儿童持续性头痛需要考虑CT,即使没有焦点神经缺陷.
- 及时诊断和抗凝治疗对于有利的结果至关重要.
相关概念视频
Inflammatory Bowel Disease I: Ulcerative Colitis
326
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
326
Esophageal Varices-II: Clinical Features and Management
144
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
144
Aneurysm II: Clinical Manifestations and Diagnostic Studies
24
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
24
Drugs for Treatment of Ulcerative Colitis in IBD
239
Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
239
Inflammatory Bowel Disease V: Surgical Management
217
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
217
Peptic Ulcer Disease II: Pathophysiology
856
Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
856


