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Michael J Wons1, Avani Vaghela1, Amna Khalid1

  • 1Department of Biomedical Sciences, Rocky Vista University, Ivins, UT 84738, USA.

Reports (MDPI)
|July 29, 2025
PubMed
概括

一个罕见的严重神经病变发生在疹子子单元 (HZ/su) 疫苗 (Shingrix) 后. 本报告强调了记录罕见疫苗不良事件的重要性,以更好地评估风险.

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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

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Major Somatic Sensory Pathways01:28

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While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
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