通过过度训练导致的行为不灵活性是由背侧条形体mGluR1/5信号传导能力的降低介导的

Vincent Paget-Blanc1, Anna Cavaccini1, Alessandra Longaretti1

  • 1Neuromodulation of Cortical and Subcortical Circuits Laboratory, Istituto Italiano di Tecnologia, Genova, Italy.

PLoS biology
|July 29, 2025
PubMed
概括

过度训练小鼠导致不灵活的行为,原因是背侧条纹体中mGluR5受体信号减少. 这种分子变化损害了适应新的行动结果突发事件的能力.

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