严重创伤性脑损伤后手术后下肢深静脉血栓的危险因素:系统性审查和元分析
Min-Ling Mo, Ya-Juan Zhang1, Da-Hong Zhai1
1Department of Nursing, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.
Shock (Augusta, Ga.)
|July 29, 2025
概括
这项系统性审查确定了严重创伤性脑损伤 (sTBI) 患者手术后下肢深静脉血栓症 (LEDVT) 的11个显著风险因素. 晚年,机械呼吸和输血是主要预测因素之一.
科学领域:
- 医学研究 医学研究
- 临床结果 临床结果
- 静脉血栓塞栓症是一种静脉血栓塞栓症.
背景情况:
- 严重创伤性脑损伤 (sTBI) 患者面临手术后并发症的风险增加.
- 下肢深静脉血栓塞 (LEDVT) 在这个易受伤害的人群中是一个重大问题.
- 识别风险因素对于有效的预防策略至关重要.
研究的目的:
- 系统地评估患有sTBI的患者手术后LEDVT的危险因素.
- 综合现有研究的证据,以告知临床实践.
- 在sTBI中提供LEDVT预测器的全面概述.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 搜索了多个英语和中文数据库,截至2024年12月12日.
- 包括13项研究 (n=777,327),包括质量评估和随机效应元分析.
主要成果:
- 确定了手术后LEDVT的11个显著风险因素.
- 关键因素包括晚年,使用脱水剂,机械通风,D-二次数升高,多创伤,高血压,长时间的手术,高BMI,深静脉导管,更长的住院时间和输血.
- 格拉斯哥昏迷度数和糖尿病不是显著的危险因素.
结论:
- 高龄,机械呼吸和输血是STBI患者LEDVT的重要危险因素.
- 鉴定到的风险因素凸显了针对性预防措施的必要性.
- 个性化风险评估对于在sTBI中管理LEDVT至关重要.
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