头骨底部手术中的输血指导方针:范围审查
Carson Gundlach1, Trevor A Poulson2, Mohamed Bah3
1Weill Cornell Medical College, New York, NY 10065, USA.
概括
在骨底部手术中输血的指导方针缺乏. 血红蛋白水平为7g/dL可以指导输血,但需要进一步研究.
科学领域:
- 神经外科 神经外科
- 输血医学 输血医学
- 基于证据的医学基于证据的医学.
背景情况:
- 在成年人头骨底部神经外科手术中,血液产品输血缺乏一致的指导方针.
- 需要基于证据的考虑来指导输血实践.
研究的目的:
- 综合当前关于在头骨底部手术中输血血液产品的文献.
- 为输血管理提供初步基于证据的考虑.
主要方法:
- 使用PubMed,科学网络和SCOPUS进行的范围审查.
- 遵守系统审查和元分析的优先报告项目 扩展范围审查 (PRISMA-ScR) 准则.
- 包含了11个相关条款.
主要成果:
- 老年患者和患有并发症 (心血管疾病,糖尿病,凝血病) 的患者更有可能接受输血.
- 输血患者在医院住院时间较长 (15.5-19.9天与4.9-8天).
- 贫血与增加的死亡率 (3.4%对比0.8%) 和更长的住院时间 (4.6对比1.4天) 相关.
结论:
- 血红蛋白值为7g/dL可能是头骨底部手术中输血的合理起点.
- 本建议基于有限的证据,需要进行前性验证.
- 进一步的研究是有必要的,以建立最终的输血指南.
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