对加拿大实践中的治疗进行更新
Samantha Keow1, Grace Xiong1, Mohannad Abu-Hilal2
1Medical student in the Michael G. DeGroote School of Medicine at McMaster University in Hamilton, Ont.
Canadian family physician Medecin de famille canadien
|July 29, 2025
概括
2024年美国皮肤病学会 (AAD) 的指导方针为加拿大提供了更新的 (AV) 管理策略. 对于局部甲氧化物和口服异二甲,有强烈的建议,并仔细考虑不同患者群体.
科学领域:
- 皮肤病学 皮肤病学
- 药理学 药理学是指药理学的学科.
- 基于证据的医学是基于证据的医学.
背景情况:
- 普通 (AV) 是一种常见的皮肤疾病,需要更新管理指南.
- 2024年美国皮肤病学会 (AAD) 的指导方针为AV护理提供了新的建议.
- 加拿大皮肤科医生需要指导来应用这些新的AAD指南来实践.
研究的目的:
- 更新和应用2024年AAD指南,用于加拿大的 (AV) 管理.
- 总结当前基于证据的实践,治疗方法和AV管理的新兴趋势.
- 将新的指导方针与加拿大特定治疗的可用性相结合.
主要方法:
- 在美国,MEDLINE和Embase对9岁以上患者的AV治疗进行文献搜索.
- 使用Cochrane风险偏见工具进行质量评估,并通过GRADE获得证据确定性.
- 搜索了加拿大联邦药物和健康产品注册表的可用治疗方法.
主要成果:
- 强烈推局部氧化,抗生素和固定剂量组合.
- 有条件的推用于局部的视网类药物,clascoterone,酸和azelaic酸.
- 强烈推口服多克西环素和异丁氨酸;条件为米诺环素,口服避孕药和螺旋. 伊索特里诺因是治疗严重的黄金标准;治疗痕风险的内溶性皮质类固醇. 特殊的人群需要量身定制的方法.
结论:
- 2024年AAD指南为加拿大AV管理提供了一个强大的框架.
- 轻微的AV用局部治疗;中度至重度的病例通常需要口服药物.
- 不建议单独使用抗生素治疗;建议使用氧化进行联合治疗以对抗耐药性. 多模式治疗是最受欢迎的.
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