超加工食品消费与肺癌风险之间的关联:基于人口的队列研究
Kanran Wang1,2, Junhan Zhao3, Dingyi Yang1,2
1Radiation Oncology Center, Chongqing Cancer Hospital, Chongqing, China.
Thorax
|July 29, 2025
概括
超加工食品 (UPF) 的消费量增加与肺癌风险增加有关,包括非小细胞肺癌 (NSCLC) 和小细胞肺癌 (SCLC). 限制UPF摄入量可能会给健康带来好处.
科学领域:
- 营养流行病学 营养流行病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 有限且不一致的证据表明超加工食品 (UPF) 与肺癌风险之间的关联.
- 调查这种联系对于公共卫生建议至关重要.
研究的目的:
- 确定UPF消费是否与肺癌风险增加有关,特别是非小细胞肺癌 (NSCLC) 和小细胞肺癌 (SCLC).
主要方法:
- 利用前列腺,肺,结肠直肠和卵巢 (PLCO) 癌症查试验的数据.
- 使用经过验证的饮食史问卷评估饮食摄入量,并根据NOVA分类对食品进行分类.
- 采用多变量考克斯回归来分析UPF消费与肺癌风险之间的关联,并对混因素进行调整.
主要成果:
- 总共有1706例肺癌病例 (1473例NSCLC,233例SCLC) 在12.2年内在101,732名成年人中被发现.
- 与消费最低的个人相比,消费最高的UPF的人患肺癌 (HR=1.41),NSCLC (HR=1.37) 和SCLC (HR=1.44) 的风险明显更高.
- 在子组和灵敏度分析中,结果仍然显著.
结论:
- 更高的UPF摄入量与肺癌,NSCLC和SCLC的风险增加有关.
- 研究结果支持减少UPF消费的健康益处.
- 建议对不同种群进行进一步的研究.
关键词:
肺癌 肺癌 是 一种 肺癌.更多相关视频
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