在荷兰初级医疗保健中对奎蒂阿平的处方模式和指示:一项回顾性数据库研究研究
Büsra G Cinar1, Suzanne A Ligthart2, Hugo Ajm de Wit1
1Department of Cinical Pharmacy, Canisius Wilhelmina Hospital, Nijmegen, the Netherlands.
BJGP open
|July 29, 2025
概括
在荷兰,为睡眠问题开出非标签的奎蒂亚平处方正在增加. 这一趋势凸显了对其驱动因素和长期影响的进一步研究的需要.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 临床药房 临床药房
背景情况:
- 奎蒂阿平已被批准用于治疗精神分裂症,双相情感障碍和严重抑郁症.
- 它的镇静作用导致非标签用于失眠,尽管潜在的副作用.
- 全球越来越多的奎蒂亚平使用需要检查处方模式.
研究的目的:
- 调查荷兰初级医疗保健中奎蒂亚平处方趋势.
- 专注于非标签使用提氨酸的流行率和适应症.
主要方法:
- 荷兰 (2003-2022) 国家和区域处方数据的回顾性分析.
- 对抗精神病症趋势的检查和详细的按剂量分类的奎提阿平处方模式.
- 从患者记录中分析处方指示,包括自由文本数据.
主要成果:
- 在全国范围内 (2003-2022年) 奎蒂阿平的使用增加了13倍,推动了整体抗精神病药物的使用.
- 区域性奎提亚平的使用量增加了3.3倍 (2012-2021年),较低剂量 (<100毫克/天) 的使用量增加.
- 在2020-2022年,76.6%的新的奎提阿平处方是非标签的,其中46.9%是睡眠问题.
结论:
- 在荷兰,非标签的奎蒂亚平处方,特别是用于睡眠问题,正在增加.
- 尽管存在临床指南和警告,这种趋势仍然存在.
- 需要进一步调查这种处方做法的原因和后果.
关键词:
药物处方 药物处方 药物处方荷兰 荷兰 荷兰 荷兰 荷兰抗精神病药物 抗精神病药物在标签之外使用.初级医疗保健是一项主要的医疗保健.奎蒂亚平因 (quetiapine) 是一种类型的药物.回顾性研究是回顾性研究.更多相关视频
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