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Updated: Sep 13, 2025

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自克林干扰素中毒中介于BRCA1/2-突变癌症中的ADAR1-依赖合成致死性

Roman M Chabanon1,2,3,4, Liudmila Shcherbakova5,6, Magali Lacroix-Triki7,8

  • 1The ERC (Epi)Genetic Vulnerabilities in Solid Tumors and Sarcoma Laboratory, Inserm Unit UMR981, Gustave Roussy, Villejuif, France. roman.chabanon@gustaveroussy.fr.

Nature communications
|July 29, 2025
PubMed
概括

抑制ADAR1是一种潜在的癌症治疗方法. 研究人员发现BRCA1/2突变与ADAR1产生合成致命性,为BRCA1/2突变癌症提供了新的治疗策略.

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