客观和主观睡眠时间,抑郁症状和全因死亡率之间的关联:研究途径
Yuan Zeng1, Tanshu Liu2, Rui Qiu2
1Department of Acupuncture and Moxibustion, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, 364000, China. 18020628091@163.com.
BMC psychiatry
|July 29, 2025
概括
较短的主观睡眠时间增加了死亡风险,抑郁症状发挥了重要的调解作用. 客观睡眠持续时间也显示了与死亡率的J形联系,强调了睡眠健康的重要性.
科学领域:
- 睡眠科学 睡眠科学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 睡眠障碍与抑郁症和死亡率有关.
- 之前的研究还没有量化地比较睡眠时间对死亡率的客观和主观影响.
- 抑郁症状在睡眠死亡相关性中的调解作用需要进一步研究.
研究的目的:
- 量化比较客观和主观睡眠时间对所有原因死亡率的影响.
- 检查抑郁症状在睡眠时间和死亡率之间的关系中的调解作用.
- 分析2011-2014年国家健康和营养检查调查 (NHANES) 的数据.
主要方法:
- 使用结构方程建模 (SEM) 来分析NHANES数据 (2011-2014).
- 使用患者健康问卷 (PHQ-9) 评分评估抑郁症状.
- 在7838名参与者中,研究了客观/主观睡眠时间,抑郁症状和全因死亡率之间的关联.
主要成果:
- 确定了客观睡眠时间和死亡风险之间的J形关系.
- 揭示了主观睡眠时间和死亡风险之间的U形关系.
- 发现抑郁症状介导了主观睡眠时间缩短 (<7h) 和死亡率之间的关系的40.63%,但客观睡眠时间 (≥7h) 只有2.10%.
结论:
- 对客观和主观睡眠时间与死亡率的J形和U形相关性得到证实.
- 抑郁症状显著调解了主观睡眠时间缩短与死亡率之间的联系.
- 强调需要解决同时发生的主观睡眠不足和抑郁症的需要.
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