怀孕期间的维生素D状态和4岁儿童的神经认知功能
Núria Voltas1,2,3,4, Esther Cendra-Duarte1,3,5, Josefa Canals1,2,3
1Research Group on Nutrition and Mental Health (NUTRISAM), Universitat Rovira i Virgili, Tarragona and Reus, Spain.
Pediatric research
|July 29, 2025
概括
怀孕期间母亲的维生素D缺乏与儿童神经发育不佳有关,影响视觉运动技能和执行功能. 确保足够的维生素D (25-基维生素D) 水平支持儿童早期的最佳认知发育.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 公共卫生 公共卫生
背景情况:
- 低维他命 D 在怀孕期间很常见,可能会对胎儿大脑发育产生负面影响,可能导致神经认知缺陷.
- 这项研究研究了母亲的维生素D状况与儿童的神经认知结果之间的关系.
研究的目的:
- 调查产前血清25-氧维生素D (25(OH) D) 水平与4岁儿童神经认知功能之间的关联.
- 为了确定在怀孕期间受到母亲维生素D状态影响的特定神经认知领域.
主要方法:
- 测量母亲血清25(OH) D是在289个母婴对的第一个和第三个三个月.
- 儿童的神经认知功能在4岁时使用WPPSI-IV,NEPSY-II和BRIEF-P进行了评估,并得到了父母的意见.
- 控制了包括社会人口统计,生活方式,母亲健康和父母智力在内的混因素.
主要成果:
- 在整个怀孕期间缺乏25-OH-D与视觉运动精度降低相关 (NEPSY-II).
- 第三季度维生素D不足与执行功能较差有关,包括工作记忆 (WPPSI-IV),元认知指数和抑制 (BRIEF-P).
结论:
- 在怀孕期间保持适当的母体25~OH) D水平对于促进儿童最佳神经认知发育至关重要.
- 研究结果强调,需要采取公共卫生措施,监测和确保孕妇在怀孕期间摄取足够的维生素D,以支持婴儿的神经发育.
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