通过使用Accordion重度分级系统对BPH/LUTS进行Rezum和Urolift并发症的比较
Kevin McVary1, Bronwyn Long1, Amandip Cheema1
1Center for Male Health, Department of Urology, Stritch School of Medicine, Loyola University Medical Center, Maywood, IL, USA.
International urology and nephrology
|July 30, 2025
概括
在BPH/LUTS治疗中,Rezum和Urolift显示了类似的短期并发症. 然而,与Urolift相比,Rezum的长期并发症率和严重程度负担在五年内明显较低.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 最少侵入性的手术
- 良性前列腺增生症 (BPH) 管理
背景情况:
- 良性前列腺增生 (BPH) 和下泌尿道症状 (LUTS) 影响着老年男性人口的很大一部分.
- 像Rezum和Urolift这样的微创手术疗法 (MIST) 为传统治疗提供了替代方案.
- 对并发症概况的标准化比较对于明智的临床决策至关重要.
研究的目的:
- 为了比较Rezum和Urolift的短期和长期并发症概况.
- 为了评估并发症的严重程度,使用协奏曲严重程度分级系统.
- 为了评估两种手术的加权术后发病率指数 (PMI).
主要方法:
- 从Rezum和Urolift的关键随机试验中分析已公布的数据.
- 泌尿科医生对并发症严重程度的独立分级.
- 评估短期 (3个月) 和长期 (5年) 的并发症率.
- 计算权重的PMI和蒙特卡洛模拟用于不确定性分析.
主要成果:
- 短期PMI值是可以比较的:Rezum (0.091) 和Urolift (0.092).
- 常见的短期并发症包括失尿症,出血症,疼痛和尿急症.
- 在5年内,Rezum的累积并发症率为15.4%,而Urolift的累积并发症率为33.6%.
- 与Urolift (0.165) 相比,Rezum的5年PMI显着较低 (0.055),这表明Urolift的长期负担是Urolift的三倍.
结论:
- 在Rezum和Urolift的长期并发症概况中存在显著差异.
- 在并发症发生率和严重程度方面,Rezum表现出更有利的长期安全概况.
- 这些发现可以指导临床选择用于BPH/LUTS治疗的MIST.
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