Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Phylogeny01:23

Phylogeny

47.5K
Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
47.5K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

6.2K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
6.2K
Phylogenetic Trees03:21

Phylogenetic Trees

46.7K
Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.
46.7K
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

145
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
145
Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

4.3K
Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
4.3K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

7.4K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
7.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A PLUM Job: Peptide modeLs for Understanding and engineering antiMicrobial therapeutics.

bioRxiv : the preprint server for biology·2026
Same author

Pathogenesis and Transmission of a Reassorted H1 Influenza A Virus Detected in North American Swine.

Influenza and other respiratory viruses·2026
Same author

Active surveillance for influenza A virus in swine reveals within-farm reassortment and cocirculation of distinct subtypes and genetic clades.

Veterinary microbiology·2025
Same author

Revealing Reassortment in Influenza A Viruses with TreeSort.

Molecular biology and evolution·2025
Same author

Transmission and Pathologic Findings of Divergent Human Seasonal H1N1pdm09 Influenza A Viruses Following Spillover Into Pigs in the United States.

Influenza and other respiratory viruses·2025
Same author

Computing generalized cophenetic distances under all Lp norms: A near-linear time algorithmic framework.

PLoS computational biology·2025

相关实验视频

Updated: Sep 13, 2025

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

35.5K

菲洛-rs:一个可扩展的遗传学分析库在生.

Sriram Vijendran1, Tavis Anderson2, Alexey Markin2

  • 1Department of Computer Science, Iowa State University, Ames, IA, 50011, USA. sriramv@iastate.edu.

BMC bioinformatics
|July 30, 2025
PubMed
概括

Phylo-rs 是一个新的 Rust 库,用于快速,记忆效率高的遗传学分析. 它有助于从大型测序数据集中解读进化关系,并有助于基因组流行病学和疫苗开发.

关键词:
图书馆 图书馆 图书馆 是一个人类遗传学 是一个学科.防 防 是一种在WebAssembly中使用.

更多相关视频

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

16.0K
A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq
07:09

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq

Published on: May 28, 2021

9.7K

相关实验视频

Last Updated: Sep 13, 2025

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

35.5K
Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

16.0K
A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq
07:09

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq

Published on: May 28, 2021

9.7K

科学领域:

  • 计算生物学 计算生物学
  • 生物信息学是一种生物信息学.
  • 进化生物学 进化生物学

背景情况:

  • 下一代和长时间读取的测序产生了大量的家族遗传数据.
  • 有效的计算库对于分析这些数据和开发专门的算法至关重要.
  • 遗传学比较生物学需要强大的工具来推断进化关系.

研究的目的:

  • 介绍Phylo-rs,一个基于Rust的库,用于遗传学分析和推断.
  • 为大规模的遗传学研究提供快速,记忆效率高,可扩展的工具.
  • 促进先进的遗传学算法的开发和传播.

主要方法:

  • 在Rust中开发了Phylo-rs,利用其速度,内存安全性和WebAssembly支持.
  • 实现了内存高效的数据结构和基本的遗传学算法.
  • 与现有的流行的族系学图书馆进行了可扩展性分析.

主要成果:

  • 与已建立的图书馆相比,Phylo-rs在关键算法上表现出同等或更高的性能.
  • 应用Phylo-rs分析猪流感A病毒多样性,确定疫苗向的扩大群体.
  • 通过将MCMC树空间可视化为基因组流行病学应用,增强了家族遗传推断.

结论:

  • 菲洛-rs支持创建先进的遗传学分析软件.
  • 它促进了进化生物学理论进步的实际应用和传播.
  • Phylo-rs是开源的,促进了可访问性和协作开发.