听力损失与全身小血管血管炎之间的关联:跨疾病类型的听力学方面
Vija Vainutienė1, Eugenijus Lesinskas2, Tatjana Ivaškienė1
1State Research Institute Centre for Innovative Medicine, Santariškių str. 5, LT-08406 Vilnius, Lithuania.
Medicina (Kaunas, Lithuania)
|July 30, 2025
概括
系统性小血管血管炎 (SV) 在ANCA阳性患者中经常导致听力损失,特别是神经传感类型. 常规的听力学评估对于早期发现和管理SV听力障碍至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 免疫学 免疫学 免疫学
背景情况:
- 系统性小血管血管炎 (SV) 涵盖了罕见的自身免疫性疾病,表现不同.
- 听觉受体症状在SV中很常见,使诊断和治疗复杂化.
- 了解SV患者的听力功能对于患者管理至关重要.
研究的目的:
- 评估SV患者的听觉功能和语音感知.
- 探索听力障碍与SV的临床参数之间的相关性.
- 为了确定SV患者的听力损失的患病率和类型.
主要方法:
- 一组40名SV患者接受了全面的听力学评估.
- 方法包括耳镜检查,耳测量,纯音声听力测量和语音听力测量.
- 使用R软件 (4.3.1版本) 进行统计分析.
主要成果:
- 在50%的SV患者中发现了感觉神经听力损失,主要影响ANCA阳性个体.
- 丧失听力最常见的是死角性血管病变 (60%).
- 77.5%的患者报告听力问题,20%的患者将其作为初始症状体验.
结论:
- 感官神经听力损失是SV的重要并发症,特别是在ANCA阳性病例中.
- 建议所有SV患者进行例行听力学查.
- 早期识别听力损失可以改善患者的治疗结果和管理策略.
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