临床和流行病学特征和Chryseobacterium物种的抗菌感应模式:一个范围审查
1Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 2, Min-Sheng Road, Dalin Town, Chiayi County 622401, Taiwan.
Medicina (Kaunas, Lithuania)
|July 30, 2025
概括
菌菌种感染率正在上升,特别是在患有并发病的老年患者中. 宿主因素,而不是细菌毒性,影响结果,米诺环素和三甲烯/硫甲醇对Chryseobacterium indologenes表现出敏感性.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 菌菌种的感染很少见,但正在增加,特别是在患有心血管疾病,糖尿病和恶性瘤等并发症的老年患者中.
- 大多数Chryseobacterium感染是医院获得的,结果通常很差,抗菌药物治疗的影响有限.
- 了解抗微生物敏感性模式对于管理这些具有挑战性的感染至关重要.
研究的目的:
- 审查克里西奥细菌物种感染的临床和流行病学特征.
- 分析Chryseobacterium物种的抗微生物敏感性模式.
- 为了确定影响克里西奥细菌感染患者结果的因素.
主要方法:
- 在PubMed和Web of Science数据库中进行了全面的文献搜索.
- 审查了1990年1月至2025年2月期间发表的研究,调查了Chryseobacterium对抗菌素敏感性的研究.
- 关于感染发生率,隔离地点,临床特征和抗生素图的数据被提取和分析.
主要成果:
- 氏菌感染的发病率正在增加,主要是患有并发病的老年人.
- 不适当的抗微生物治疗比死亡率更为常见,这表明抗生素有效性有限.
- 观察到Cryseobacterium indologenes和Cryseobacterium gleum对各种抗生素的敏感率有所变化,米诺环素和trimethoprim/sulfamethoxazole对C. indologenes具有更好的活性.
结论:
- 宿主因素显著地影响了克里西奥细菌感染患者的结果,而不是细菌的毒性.
- 米诺环素和三甲/硫甲醇显示出对Chryseobacterium indologenes分离物的显著敏感性.
- 有效的管理需要将临床专业知识与对宿主因素和特定抗菌素敏感性的知识相结合.
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