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在慢性鼻炎的过程中,共生菌对细菌菌群的影响

Karolina Goroszkiewicz¹, Grażyna Lisowska², Grażyna Stryjewska-Makuch¹

¹Department of Laryngology and Laryngological Oncology, Leszek Giec Upper-Silesian Medical Centre of the Silesian Medical University, 40-635 Katowice, Poland.

Medicina (Kaunas, Lithuania)

|July 30, 2025

概括

口服共生补充剂可能有助于减少慢性鼻炎 (CRS) 患者的致病细菌,这些患者正在接受内镜性鼻手术 (ESS). 这种方法可能会减少对术后抗生素的需求.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
微生物学微生物学
免疫学免疫学免疫学

背景情况:

慢性鼻炎 (CRS) 与微生物失衡 (疾病) 有关.
协生菌 (益生菌+益生菌) 在调节微生物群和免疫反应方面表现出潜力.
这项研究调查了共生菌对接受手术的CRS患者的鼻微生物群的影响.

研究的目的:

评估口服共生补充剂对鼻微生物群组成的影响.
评估共生菌在内镜鼻手术 (ESS) 后对致病性细菌殖民的影响.
确定协生菌是否减少了CRS患者手术后抗生素治疗的需要.

主要方法:

一项多中心回顾性研究,涉及425名接受ESS的成年CRS患者.
干预组在外科手术期间接受了6-8周的共生菌;对照组没有.
分析了细菌学样本,并进行了群体之间的统计比较.

主要成果:

协生菌的使用在ESS后显著减少了致病性细菌殖民地.
凝聚酶负型葡萄球菌在协生组中更频繁.
同生菌组所需的术后抗生素治疗显著减少 (p < 0.05).
这两组在ESS后都显示了格兰阳性菌群的增加和格兰阴性细菌的减少.

结论:

同生菌补充剂可能会积极改变鼻微生物群,并在ESS后减少致病细菌.
协生菌作为CRS的辅助疗法表现有前途.
研究结果表明,共生菌可能会减少在CRS管理中对术后抗生素的依赖.

关键词:

慢性鼻鼻炎是什么益生菌是一种益生菌.回顾性研究是回顾性研究.综合生物 synbiotics 综合生物

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