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Updated: Sep 13, 2025

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purin-hydrazone支架作为潜在的EGFR/HER2双抑制剂

Fatemah S Albalawi1,2, Mashooq A Bhat2, Ahmed H Bakheit2

  • 1School of Pharmacy, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

Pharmaceuticals (Basel, Switzerland)
|July 30, 2025
PubMed
概括

新的含精氨酸的氨酸通过准表皮生长因子受体 (EGFR) 和人体表皮生长因子受体2 (HER2) 来表现出强大的抗癌活性. 化合物19a,16b和22b表现出显著的抗增殖作用和激酶抑制,提供了有前途的治疗候选者.

关键词:
欧洲农业基金会 (EGFR) 是一个.在EGFR和HER2驱动的癌症中.在HER2中,HER2是HER2.癌症 癌症 癌症 癌症 癌症埃尔洛丁尼布 (erlotinib) 是一种药物.拉帕提尼布 (lapatinib) 是一种治疗方法.含有 purin/hydrazone 的化合物.

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