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Updated: Jun 16, 2026

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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激光微干扰仪用于API可溶性和相位平衡:达鲁纳维尔作为一个案例

Veronika Makarova1, Mark Mandrik1,2, Sergey Antonov1

  • 1A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Leninsky pr. 29, 119991 Moscow, Russia.

Pharmaceutics
|July 30, 2025
PubMed
概括

激光微干扰度准确地确定无形活性药物成分 (API) 的热力学可溶性和相位行为. 这种方法有助于选择辅助剂,并预测药物开发的配方稳定性.

关键词:
汉森溶解度参数 汉森溶解度参数药品中的活性药物成分.无形的达鲁纳维尔溶解动力学 溶解动力学在药物开发的早期阶段.激光微干扰计是微干扰计.阶段图 阶段图 阶段图热力学可溶性 热力学可溶性

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