在有或没有代谢综合征的个体中,酒衍生 (多) 醇代谢:比较的饮食干预
Daniel Hinojosa-Nogueira1,2, Cristina María Díaz-Perdigones1,2, María José García-López1,3,4
1Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma, BIONAND, 29590 Málaga, Spain.
在有或没有代谢综合征 (MetS) 的个体中,酒消费对 (多) 代谢的影响不同. 这些化合物可能通过调节特定的途径来影响代谢健康,这表明潜在的心血管益处.
科学领域:
- 营养生物化学 营养生物化学
- 代谢研究 代谢研究
背景情况:
- 低酒精含量发酵饮料与心血管健康益处有关.
- 聚醇被认为是这些健康改善的媒介.
- 这些影响背后的机制需要进一步阐明.
研究的目的:
- 研究控制酒消费对多醇代谢的影响.
- 为了比较具有和没有代谢综合征 (MetS) 的个体中的多代谢.
主要方法:
- 一项为期6周的受控干预研究,共20名参与者 (MetS和对照).
- 标准化的酒消费被管理.
- 分析了尿液中的化合物.
主要成果:
- 慢性酒消费改变了尿中的性特征,尤其是hesperetin结合物和降解的黄类/类.
- 代谢综合征 (MetS) 和对照组表现出不同的基线多烯特征和代谢模式.
- 差异包括在健康人群中增加的纳灵宁II期结合物和在MetS参与者中增加的细菌黄类催化剂.
- 发现了化合物和代谢/人类学变量之间的相关性.
结论:
- 酒衍生的多醇根据代谢健康状况而被不同地代谢.
- 这些代谢物可能通过途径调节促进代谢健康益处.
- 研究结果表明,酒多在心血管健康中通过代谢途径发挥作用.
更多相关视频
11:06Network Pharmacology Prediction and Metabolomics Validation of the Mechanism of Fructus Phyllanthi against Hyperlipidemia
Published on: April 7, 2023
10:31An Experimental Model of Diet-Induced Metabolic Syndrome in Rabbit: Methodological Considerations, Development, and Assessment
Published on: April 20, 2018
相关概念视频
Overview of Carbohydrate Metabolism
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
Phase I Reactions: Oxidation of Aliphatic and Aromatic Carbon-Containing Systems
Oxidation reactions are fundamental in aromatic carbon-containing systems. An example is the hydroxylation of phenobarbital, a process that transforms it into...
Inborn Errors of Metabolism
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Cholesterol: Significance and Regulation
Considering cholesterol and...
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
