伴随疾病在COVID-19严重性中的作用
Sandra König1, Ugne Vaskyte1,2, Maria Boesing1,2
1University Institute of Internal Medicine, Cantonal Hospital Baselland, 4410 Liestal, Switzerland.
肥胖,糖尿病和高血压等并发症显著增加了住院患者的COVID-19临界结果. 没有并发症的患者经历了最低的严重疾病和并发症率.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 内部医学 内部医学
背景情况:
- COVID-19导致了全球显著的发病率和死亡率.
- 了解伴随性疾病对COVID-19结果的影响对于患者管理至关重要.
- 有限的数据存在于影响COVID-19严重程度的并发症,在多个爆发浪潮的多个瑞士队伍中.
研究的目的:
- 探索伴随性疾病对住院患者COVID-19严重性的作用.
- 评估瑞士队列中并发症和特定的住院并发症之间的关联.
主要方法:
- 在瑞士巴塞尔州州立医院进行了回顾性,观察性,单中心研究 (2020年3月至2021年12月).
- 包括1124名因COVID-19住院的成年患者.
- 经年龄和性别调整后的后勤回归分析评估了并发症和危急状况/并发症之间的关联.
主要成果:
- 76%的患者至少有一种并发症;常见的包括高血压 (47%),肥胖 (27%) 和糖尿病 (24%).
- 肥胖,糖尿病,高血压,心律失常和COPD与严重的COVID-19状况有关.
- 没有并发症的患者的危急病情 (5.3%) 和并发症 (10.2%) 发生率明显较低.
结论:
- 特定的并发症是关键COVID-19临界结果的关键风险因素,与之前的研究一致.
- 在评估的并发症中,喘对COVID-19疾病严重程度的影响最小.
- 未来的研究应该调查特定并发症患者的联合并发症效应和长期COVID-19结果.
更多相关视频
08:41Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
06:55Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
相关概念视频
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Pneumonia II: Pathophysiology
