评估中国南宁老年人免费PPV23疫苗接种:成本效益分析
Zhengqin Su1,2, Linlin Deng3, Dan Luo1,2
1School of Public Health and Management, Guangxi University of Chinese Medicine, Nanning 530200, China.
Vaccines
|July 30, 2025
概括
免费为老年人提供23性肺炎球菌多糖体疫苗 (PPV23) 比自付更具成本效益,尽管这两种方法都不符合传统的基准. 这表明了区域卫生政策的潜在价值.
科学领域:
- 卫生经济学 卫生经济学
- 疫苗学 疫苗学 疫苗学
- 公共卫生政策 公共卫生政策
背景情况:
- 肺炎球菌病对老年人造成重大健康负担.
- 疫苗接种策略的成本效益需要地方评估.
研究的目的:
- 为了比较免费,自我资助和没有23-valent肺炎球菌多糖体疫苗 (PPV23) 对60岁以上的成年人的成本效益.
- 根据成人疫苗接种的区域卫生政策决策提供信息.
主要方法:
- 一个决策树-马尔科夫模型被用于经济评估.
- 当地的流行病学和成本数据被纳入了3%的折扣率.
- 对疫苗有效性和治疗成本等关键参数进行了敏感性分析.
主要成果:
- 免费 (0.075) 和自筹 (0.015) PPV23疫苗接种的效益成本比低于1.
- 免费接种疫苗的策略带来了更高的净收益 (399651.32美元) 和更低的ICER (1.47美元).
- 疫苗的有效性和治疗成本对经济结果产生了重大影响.
结论:
- 在南宁,无论是免费的还是自筹的PPV23疫苗接种都没有达到传统的成本效益值.
- 与自我资助的疫苗接种相比,免费的PPV23疫苗接种显示出更高的经济效率.
- 建议考虑将老年人纳入区域卫生政策.
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