相关实验视频

Updated: Sep 13, 2025

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

在软组织肉瘤中F-FDG PET/CT参数的预后意义:系统性审查和元分析

Shaoli Li^1,2,3, Rui Bai^1,2,3, Hui Wang⁴

¹Department of Medical Oncology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, China.

Cancer imaging : the official publication of the International Cancer Imaging Society

|July 30, 2025

概括

在18F-氧葡萄糖正子发射断层扫描/计算机断层扫描 (18F-FDG PET/CT) 上的最大标准化吸收值 (SUVmax) 预测软组织肉瘤 (STS) 的预后不佳. 代谢性瘤体积 (MTV) 也与STS患者的整体存活率降低相关.

科学领域:

在瘤学瘤学.
核医学是一种核医学.
放射学放射学是一门学科.

背景情况:

在软组织肉瘤 (STS) 中,18F-氧葡萄糖正子发射断层扫描/计算机断层扫描 (18F-FDG PET/CT) 参数的预后价值受到争议.
准确的预后标记对于定制STS治疗策略至关重要.

研究的目的:

在STS患者中系统评估18F-FDG PET/CT参数的预后意义.
确定SUVmax,MTV和TLG与总生存率 (OS) 和无进展生存率 (PFS) 的相关性.

主要方法:

系统审查和对2024年1月1日之前发表的研究进行元分析.
包括19项涉及962名STS患者的研究.
使用随机效应模型计算95%置信区间 (CI) 的聚合危险比率 (HR).

主要成果:

较高的SUVmax与较差的OS (HR: 1.17) 和PFS (HR: 1.62) 有显著的关联.
增加的代谢性瘤体积 (MTV) 与减少的OS显著相关 (HR:1.87).
总损伤糖解 (TLG) 没有表明与OS有显著的关联 (HR:2.00).

结论:

18F-FDG PET/CT衍生SUVmax是OS和PFS中STS预后不佳的重要预测因素.
此外,MTV也是STS中OS的重要预后指标.
在STS中TLG的预后作用需要进一步调查.

关键词:

18F-Fluorodeoxyglucose正子发射断层扫描/计算机断层扫描进行元分析分析.预测预测预测预测预后预测预测软组织肉瘤是软组织肉瘤.

更多相关视频

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Published on: July 21, 2018

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

相关概念视频

Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...