美国成年人的氧化平衡得分和胆结石之间的关联:一个横截面研究
Xiaoya Chen1,2, Xiongwei Huo2, Changchun Ye2
1Department of Thoracic Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Frontiers in aging
|July 30, 2025
概括
通过氧化平衡得分 (OBS) 测量较高的抗氧化剂暴露与较低的胆结石疾病风险有关. 这表明,改变生活方式和饮食可能有助于预防胆结石.
科学领域:
- 营养与饮食学 营养与饮食学
- 流行病学 流行病学
- 氧化压力研究研究 氧化压力研究
背景情况:
- 系统性氧化应激使用氧化平衡得分 (OBS) 进行评估.
- 有限的研究存在于氧化应激和胆结石患病率之间的关系.
研究的目的:
- 为了研究氧化平衡得分 (OBS) 与美国成年人群中的胆结石患病率之间的关联.
- 探索饮食和生活方式因素对这种关联的影响.
主要方法:
- 从NHANES 2017-2020中对4,376名参与者的横截面分析.
- 通过患者健康问卷进行胆结石诊断.
- 根据16种饮食和4种生活方式因素计算OBS.
- 使用了后勤回归,子组分析和受限立方线 (RCS).
主要成果:
- 在OBS和胆结石患病率 (OR = 0.96) 之间发现了显著的反向关联.
- 在最高的OBS四分位数中,与最低四分位数 (OR = 0.65) 相比,胆结石的几率降低了35%.
- OBS的饮食和生活方式成分都显示出与胆结石风险的显著关联.
结论:
- 增加的抗氧化剂暴露,由较高的OBS表明,与美国成年人减少胆结石患病率有关.
- 研究结果支持个性化的饮食和生活方式干预,以预防胆结石.
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