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超高甘油血症引起的急性胰腺炎的血酶:一个系统的审查和病例报告的元摘要
Prashant Nasa1, Ravi Jain2, Omender Singh3
1Department of Anaesthesia and Integrated Critical Care Unit, New Cross Hospital, The Royal Wolverhampton National Health Service Trust, Wolverhampton, United Kingdom.
血酶可以有效地降低患有过高甘油血症引起的急性胰腺炎 (AP) 的患者的甘油三. 这种程序是安全的,即使在严重的病例和怀孕,导致患者的康复.
科学领域:
- 胃肠病学 胃肠病学
- 关键护理医学 关键护理医学
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 过高甘油三血是急性胰腺炎 (AP) 的重要原因之一.
- 对于管理高甘油三血症诱导的AP存在有限的证据.
- 血酶是一种潜在的治疗选择.
研究的目的:
- 系统地审查病例报告和关于高甘油三血症诱导AP的等离子体合成的系列.
- 为了评估患者的特征,降低甘油三和血合成的安全性.
- 评估血酶对AP结果的影响.
主要方法:
- 在PubMed,Science Direct,Embase和谷歌学者 (1975-2023) 的系统文献搜索.
- 纳入标准:高甘油三血症诱导的AP和血合成的使用.
- 71项涉及91名患者的研究的元总结.
主要成果:
- 大多数患者 (近75%) 患有严重的AP;20%患有复发性胰腺炎.
- 血酶显著降低了血清甘油三.
- 96.7%的患者康复,平均住院时间为11天.
结论:
- 血酶有效降低过高甘油血症诱导的AP中的甘油三.
- 该程序证明了合理的安全性,包括在严重的AP和怀孕.
- 需要进一步的随机试验来比较血酶与药理管理.
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