与久坐生活相关的腹部脂肪积累通过给予热处理的细菌细菌衍生后生物减少
Mi Wang1, Feng He1, Weishuang Meng2
1College of Animal Husbandry and Veterinary Medicine, Jinzhou Medical University, Jinzhou, China.
Frontiers in nutrition
|July 30, 2025
概括
热处理的*B. subtilis*后生物有效地减少了小的腹部脂肪和改善了小的脂质概况. 这种干预还调节了肠道微生物群和代谢物,提供了一种打击肥胖的策略.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 营养科学 营养科学
背景情况:
- 久坐不动的生活方式有助于肥胖和腹部脂肪的积累.
- 发育中的小与人类有生理上的相似之处,包括脂肪积累和消化结构.
- 小是研究肥胖和肠道健康干预的宝贵模型.
研究的目的:
- 为了研究热处理*B. subtilis*衍生后生物对小的影响.
- 评估对腹部脂肪,血液学,肠道微生物群和代谢物的影响.
- 探索后生菌在控制肥胖和改善肠道健康方面的潜力.
主要方法:
- 120天大的小被分为对照组和后生物组.
- 实验组接受了0.30%的热处理 *B. subtilis* 42天.
- 分析了腹部脂肪,血液学,肠道微生物群和代谢物概况.
主要成果:
- 后生菌的使用降低了腹部脂肪,血清胆固醇和甘油三.
- 肠道微生物群的组成发生了变化, * 细菌菌* * 斯芬戈蒙纳斯* * 克莱布西拉* 的数量减少, * 链球菌* * 维约内拉* * 艾洛巴库卢姆* * 霍乱* 的数量增加.
- 肠道类胆和血清13(S) -HODE水平降低,可能与特定细菌有关.
结论:
- 热处理的*B. subtilis*后生物可以有效地减少小的腹部脂肪积累.
- 后生物影响肠道微生物群和脂质新陈代谢,可能通过调节脂胆水平.
- 这种干预措施有望控制肥胖和改善肠道健康.
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