rTMS用于同时发生的精神病和物质使用障碍:叙述审查和未来方向
Sophia H Blyth1, Nicole L Zabik2, Amanda Krosche1
1Department of Psychiatry and Behavioral Sciences, Vanderbilt Psychiatric Hospital, Vanderbilt University Medical Center, 1601 23rd Avenue South, Nashville, TN 37232, USA.
Current addiction reports
|July 30, 2025
概括
重复性横磁刺激 (rTMS) 显示出治疗同时出现的物质使用障碍 (SUD) 和精神疾病的前景. 需要进一步的研究来确认疗效,并探索这些复杂疾病的新治疗目标.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 成 药物 药物 药物 药物
背景情况:
- 同时出现的物质使用障碍 (SUD) 在患有精神疾病的个体中很普遍,往往导致心理健康结果较差,治疗效率降低.
- 目前,没有FDA批准的治疗方法专门针对同时出现的精神病和SUD的双重诊断.
- 重复性横磁刺激 (rTMS) 是一种非侵入性脑刺激技术,目前正在作为一种潜在的治疗选择进行研究.
研究的目的:
- 综合审查现有的关于rTMS治疗精神疾病患者同时出现SUD的疗效的文献.
- 识别潜在的神经电路目标,并讨论未来对这一群体的rTMS干预的研究方向.
主要方法:
- 在PubMed,MEDLINE和谷歌学者数据库中进行了系统的文献搜索.
- 研究被手动审查,以确定所有研究对rTMS对同时发生的SUD的影响.
- 十一项研究符合审查的纳入标准.
主要成果:
- 大多数包括的研究 (7/11) 专注于治疗精神分裂症的rTMS与同时发生的SUD.
- 三项研究检查了情绪和焦虑障碍患者中SUDs的rTMS.
- 初步证据表明,rTMS可能是有效的,针对各种并发性疾病确定了潜在的神经点.
结论:
- 重复性横磁刺激 (rTMS) 在治疗同时出现的精神疾病和物质使用障碍方面表现出初步的疗效.
- 额外的研究对于验证研究结果,探索新的治疗目标和优化这种复杂的患者群体的rTMS协议至关重要.
- 未来的研究应该考虑实用方法,物质戒断,状态依赖,神经生物学标志物和治疗反应的个体预测因素.
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