Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Spongy Bone01:09

Spongy Bone

5.3K
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
5.3K
Bone Remodeling01:40

Bone Remodeling

38.5K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.5K
Bone Structure01:55

Bone Structure

49.0K
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
49.0K
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

7.5K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
7.5K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Sex differences in task engagement and lapse rate during reward learning.

bioRxiv : the preprint server for biology·2026
Same author

[Fibrin-associated large B-cell lymphoma arising in a schwannoma: report of a case].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2026
Same author

First Results on the Search for Lepton Number Violating Neutrinoless Double-β Decay with the LEGEND-200 Experiment.

Physical review letters·2026
Same author

Peripheral ameloblastoma with cervical lymph node metastasis: a case report and review of the literature.

International journal of oral and maxillofacial surgery·2026
Same author

[Economic burden of echinococcosis patients in endemic areas of western China: a meta-analysis].

Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control·2025
Same author

Can radiomics from dynamic contrast-enhanced MRI effectively predict response to neoadjuvant chemotherapy in breast cancer?: A meta-analysis.

Clinical radiology·2025
Same journal

AVA: Automated Viewability Analysis for Ureteroscopic Intrarenal Surgery.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same journal

Kidney Endoscopy Video to Preoperative CT Alignment for Depth Estimation.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same journal

Deep learning‑based cell type prediction in lung tissue from brightfield histology using CODEX-derived labels.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same journal

Reconstructing physiological signals from fMRI across the adult lifespan.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same journal

Axially Swept Light-Sheet Microscopy using scattering and fluorescence contrast mechanisms.

Proceedings of SPIE--the International Society for Optical Engineering·2026
Same journal

Analytic Bounds on GAMLSS Model Variability of Normative White Matter Brain Charts.

Proceedings of SPIE--the International Society for Optical Engineering·2026
查看所有相关文章

相关实验视频

Updated: Sep 13, 2025

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
06:59

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Published on: September 8, 2023

2.7K

一个有条件的生成扩散模型的椎骨与调节的微观结构.

X Wang1, G Shi1, A Sivakumar1

  • 1Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD USA 21205.

Proceedings of SPIE--the International Society for Optical Engineering
|July 30, 2025
PubMed
概括
此摘要是机器生成的。

一个新的生成模型可以创建可调节的合成脊椎骨,精确控制骨体积分数,厚度和间距. 这项技术使研究和开发能够实现现实的数字骨结构.

关键词:
骨的微观结构 骨的微观结构扩散模型的扩散模型综合合成 综合合成椎骨的骨头 椎骨的骨头虚拟成像是一种虚拟的成像.

更多相关视频

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
09:32

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion

Published on: April 11, 2018

9.8K
Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

9.8K

相关实验视频

Last Updated: Sep 13, 2025

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
06:59

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Published on: September 8, 2023

2.7K
Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
09:32

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion

Published on: April 11, 2018

9.8K
Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

9.8K

科学领域:

  • 生物医学工程 生物医学工程
  • 材料科学 材料科学 材料科学
  • 计算生物学 计算生物学

背景情况:

  • 脊椎骨微观结构显著影响骨完整性和骨折风险.
  • 精确的脊椎骨数字模型对于研究,模拟和开发新诊断工具至关重要.
  • 现有的合成骨制造方法可能缺乏对关键结构参数的精确控制.

研究的目的:

  • 开发一种能够生产具有可调节微观结构特征的合成脊椎骨的生成模型.
  • 为了在生成的骨样本中精确控制骨体积分数 (BV/TV),椎间板厚度 (Tb.Th) 和间距 (Tb.Sp).

主要方法:

  • 使用的扩散变压器 (DiT),是一种带有基于变压器的消噪网络的隐性扩散模型.
  • 根据目标BV/TV,Tb.Th和Tb.Sp值调节模型,以指导微结构生成.
  • 从人类大腿骨的微型CT扫描中训练了29898个ROI的模型,训练/验证比例为9:1.

主要成果:

  • 该模型生成了合成骨,很好地覆盖了现实世界的微观结构分布和视觉现实主义.
  • 在目标指标方面实现了高的皮尔森相关性:BV/TV 0.9540,Tb.Th 0.9618和Tb.Sp. 0.9835
  • 在多个模型实现中展示了稳定的微观结构特征,变化系数 (CV) 低.

结论:

  • 开发的生成模型成功地创建了现实的,可调节的数字椎骨.
  • 这项技术在虚拟临床试验中提供了潜在的应用,并为先进的图像重建建立了先验.
  • 能够对合成骨架构进行精确的控制,用于各种研究应用.