肉类和肉制品中的甲素耐药黄金葡萄球菌污染:系统审查和元分析
Lili Xing1, Mao Cheng2, Shulei Wang3
1Bacteriological Disease Laboratory, Yantai Center for Disease Control and Prevention, Yantai, Shandong, China.
Frontiers in microbiology
|July 30, 2025
概括
甲素耐药黄金葡萄球菌 (MRSA) 在全球3.72%的肉制品中被发现,这构成了食品安全风险. 在生家禽和牲畜肉类中发现更高的流行率,特别是在东地中海地区.
科学领域:
- 食品安全 食品安全
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 甲素耐药黄金葡萄球菌 (MRSA) 是一种在食用动物中发现的全球性病原体.
- 通过食物链传播给公众健康和食品安全带来了重大风险.
- 了解肉类中的MRSA患病率对于风险评估至关重要.
研究的目的:
- 系统地审查和元分析肉类和肉制品中MRSA污染的全球流行情况.
- 根据肉类,地区和时间段来确定流行率的变化.
主要方法:
- 在主要数据库 (PubMed,Embase,Web of Science,Cochrane Library) 进行全面的文献搜索,截至2024年12月.
- 使用随机效应模型进行元分析,并进行子组和灵敏度分析.
- 使用修剪和填充方法评估的出版偏差.
主要成果:
- 肉类和肉制品中MRSA的综合流行率为3.72%.
- 与加工产品 (2.84%) 相比,生家禽 (4.46%) 和牲畜肉 (3.86%) 的患病率更高.
- 东地中海地区患病率最高 (9.13%),北美患病率最低 (1.89%). 2015年后的流行率为8.33%,在考虑出版偏差后调整为14.04%.
结论:
- 肉类中MRSA污染是一个重大的公共卫生问题.
- 建议加强对生牲畜和家禽肉的监测,特别是在地中海东部和东南亚地区.
- 需要采取缓解策略来减少食品供应中的MRSA.
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