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Updated: Sep 13, 2025

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在COVID-19时代的甲状腺功能:对疾病进展和疫苗接种效应的系统审查
Maryam Zarkesh1, Maryam Sanoie1, Shabnam Heydarzadeh1
1Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
International journal of endocrinology and metabolism
|July 30, 2025
概括
COVID-19 感染可能会导致暂时的甲状腺功能障碍. 虽然很少见,但COVID-19疫苗也可能影响甲状腺功能,需要对高危人群进行监测.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- COVID-19 (冠状病毒疾病2019) 与各种系统性影响有关.
- 甲状腺功能障碍是一种潜在的并发症,需要进一步调查.
- COVID-19疫苗对甲状腺健康的影响是一个新兴的研究领域.
研究的目的:
- 为了比较COVID-19患者与健康个体的甲状腺功能测试异常.
- 为了调查COVID-19严重程度和甲状腺功能障碍之间的关系.
- 评估COVID-19疫苗对甲状腺功能和自身免疫力的影响.
主要方法:
- 从2019年12月到2023年4月,对文献进行系统审查.
- 在PubMed,科学网和Scopus进行的搜索.
- 包括观察性和病例控制性研究,重点关注COVID-19患者的甲状腺功能障碍,而这些患者之前没有甲状腺疾病.
主要成果:
- 对21项研究对COVID-19对甲状腺功能影响的分析.
- 评估了5项关于COVID-19疫苗和甲状腺健康的额外研究.
- 在COVID-19患者中识别过渡性和可逆性甲状腺功能障碍.
结论:
- 感染SARS-CoV-2可能会通过直接的病毒或免疫介导途径导致临时的甲状腺功能障碍.
- 临床医生应考虑COVID-19疫苗的潜在罕见甲状腺相关不良反应.
- 建议监测甲状腺功能,特别是在高危人群中.
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