在复杂的轻度至重度创伤性脑损伤 (TBI) 后与心血管死亡率相关的因素:A TBI模型系统研究
Shanti M Pinto1,2, Bhaskar Thakur1,2, Raj G Kumar1,2
1Author Affiliations: Department of Physical Medicine and Rehabilitation, University of Texas Southwestern Medical Center, Dallas, TX (Drs Pinto, Thakur, Bell); Department of Family and Community Medicine, Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX (Dr Thakur); Department of Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, NY, (Drs Kumar, Hicks); Jefferson Moss Rehabilitation Research Institute, Elkins Park, PA, (Drs Venkatesan, Rabinowitz); Department of Rehabilitation Medicine, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA (Drs Venkatesan, Rabinowitz); Baylor Scott & White Research Institute, Dallas, TX (Dr Driver); Baylor Scott & White Institute for Rehabilitation, Dallas, TX (Dr Driver); Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX (Dr Ding); Drucker Brain Injury Center, Jefferson Moss-Magee Rehabilitation, Elkins Park, PA (Dr Watanabe); Department of Physical Medicine & Rehabilitation, Virginia Commonwealth University, Richmond, VA (Dr Walker); Department of Physical Medicine & Rehabilitation, Richmond VA Medical Center, Central Virginia VA Health Care System, Richmond, VA (Dr Walker); Department of Physical Medicine & Rehabilitation, Indiana University School of Medicine, Indianapolis, IN (Dr Katta-Charles); Brain Injury Rehabilitation, Rehabilitation Hospital of Indiana, Indianapolis, IN (Dr Katta-Charles); Department of Physical Medicine & Rehabilitation, University of Missouri, Columbia, MO (Dr Zafonte).
心血管疾病是创伤性脑损伤 (TBI) 后的主要死亡原因. 高龄,男性性别和较低的功能评分增加了风险,而就业和私人保险提供了保护.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 创伤性脑损伤 (TBI) 可以导致长期的健康并发症.
- 心血管疾病是TBI后死亡的重要原因.
研究的目的:
- 确定与TBI后心血管死亡率相关的人口和受伤相关因素.
- 描述TBI幸存者的心血管原因死亡的风险和保护因素.
主要方法:
- 对TBI模型系统数据库参与者的回顾性分析.
- 考克斯比例危险回归被用于分析心血管相关死亡率.
- 数据包括人口统计信息,伤害特征和死亡原因编码 (ICD-9/10).
主要成果:
- 在15370名TBI参与者中,超过18%的人死亡,其中21.5%的死亡归因于心血管原因.
- 高龄,男性性别,离婚状态和较低的FIM运动分数与心血管死亡率的增加有关.
- 亚洲/太平洋岛民种族,就业,私人保险和创伤后失忆症 (PTA) >30天与心血管死亡率降低有关.
结论:
- 心血管疾病是创伤后死亡的主要原因,占五分之一以上的死亡.
- 确定的危险因素包括年龄,男性性别,离婚和功能状况较低.
- 保护因素包括就业,私人保险和创伤后记忆丧失的更长时间.


