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Updated: Sep 13, 2025

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对免疫突触的ALK2/3招募是T细胞激活和死亡所需的

Jun-Ge Shi1, Zhen-Wu Ma1, Zi-Lun Ruan1

  • 1Department of Infectious Diseases, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Zhongnan Hospital of Wuhan University, State Key Laboratory of Virology and Biosafety, Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China.

The Journal of experimental medicine
|July 30, 2025
PubMed
概括

骨形态遗传蛋白 (BMP) 受体ALK2和ALK3对于T细胞激活和AICD至关重要,独立于BMPs. 这一途径调节了效应基因诱导和免疫反应,提供了新的治疗点.

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