药监中的人工智能:用专家定义的贝叶斯网络工具进行叙事审查和实践经验
Rogério Caixinha Algarvio1,2, Jaime Conceição1,2,3, Pedro Pereira Rodrigues4
1Faculty of Sciences and Technology, University of Algarve, Faro, Portugal.
International journal of clinical pharmacy
|July 30, 2025
概括
人工智能 (AI) 通过自动化任务和改进药物不良反应 (ADR) 数据分析来增强药物监管. 虽然有希望,但人工智能集成面临着数据质量和监管障碍等挑战.
科学领域:
- 药监和药物安全 药监和药物安全
- 医疗保健中的人工智能
- 生物医学数据科学 生物医学数据科学
背景情况:
- 药物监测对于监测药物不良反应 (ADR) 和确保药物安全至关重要.
- 传统的药监方法往往是缓慢和不一致的.
- 人工智能 (AI) 在管理复杂的药物安全数据方面提供了更高的效率和准确性.
研究的目的:
- 探索AI在药物监测中的实际应用,重点关注效率,流程加速和自动化.
- 检查专家定义的贝叶斯网络对药物监督中心因果关系评估的影响.
主要方法:
- 通过使用MEDLINE,Scopus和Web of Science进行了全面的叙事文献审查.
- 关键词包括"药物监测"",人工智能"",药物不良反应"和"药物安全".
- 研究分析没有出版年或语言的限制,在2025年1月进行了搜索.
主要成果:
- 人工智能通过简化信号检测,监测和自动化ADR报告,显著改善药物监测.
- 数据挖掘和自动信号检测等技术可以加快安全信号的识别并提高数据的精度.
- 预测模型预测了副作用和药物相互作用,而贝叶斯网络优化了因果关系评估,将处理时间从几天缩短到几个小时.
结论:
- 人工智能显示出提高药物监督实践和药物安全性评估的巨大潜力.
- 人工智能的实际整合目前受到数据质量,监管障碍和算法透明度的限制.
- 需要进一步开发来克服这些挑战,以便在药监中广泛采用人工智能.
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