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实时节拍对节拍脉冲波速率估计:使用激光多普勒振动计进行质量驱动的方法
Silvia Seoni1, Patrick Segers2, Simeon Beeckman2
1Biolab, PoliTo BIOMed Lab, Department of Electronics and Telecommunications, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 , Turin, Italy. silvia.seoni@polito.it.
Medical & biological engineering & computing
|July 30, 2025
概括
一种新方法,即持续自动PWV估计 (CAPE),使用激光多普勒振动计来快速准确地实时测量动脉硬度,这是一个关键的心血管风险标志物.
科学领域:
- 生物医学工程 生物医学工程
- 心血管生理学心血管生理学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 动脉硬是心血管风险的一个关键指标.
- Carotid-femoral脉冲波速度 (cf-PWV) 是评估动脉硬性的黄金标准.
- 目前的cf-PWV评估方法可能耗时,需要专门的专业知识.
研究的目的:
- 引入和评估持续自动PWV估计 (CAPE),这是一个实时cf-PWV测量的创新框架.
- 通过使用激光多普勒振动计 (LDV) 信号来评估CAPE的可靠性和精度.
- 为了证明CAPE适合于要求快速评估心血管风险的临床应用.
主要方法:
- 开发了CAPE,这是一个整合自动信托点检测和信号质量控制的框架,用于从LDV信号中估计cf-PWV.
- 利用多通道激光振动计系统从100名高血压患者获得信号.
- 计算cf-PWV是通过将带-股骨距离除以脉冲过渡时间 (PTT) 来计算的,该距离是从LDV信号的第二导数上的模板匹配中得出的.
主要成果:
- 在对平面化度测量进行验证时,CAPE显示出高可靠性和精度,平均偏差为0.25 ± 0.77 m/s.
- 该框架提供基于自动化质量评估的PWV测量可信度评分 (可接受或优秀).
- CAPE在短短3秒内实现了cf-PWV估计,从而实现了近乎实时的分析.
结论:
- CAPE提供了一种可靠,自动化和快速的方法,用于使用LDV信号估计cf-PWV.
- 由于CAPE的速度和准确性,它非常适合实时临床心血管风险评估.
- 这项技术有可能显著改善患者群体的动脉硬性监测和管理.
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